erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
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cbl-3: a new mammalian cbl family proteinMolecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cellsIdentification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent associationCsk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancerHIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domainsHeregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistanceaxl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseAnalysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumorsInhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domainOncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gammaMolecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cellsIdentification of c-erbB-3 binding sites for phosphatidylinositol 3'-kinase and SHC using an EGF receptor/c-erbB-3 chimeraPositive and negative regulation of endogenous genes by designed transcription factorsConstitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformationAGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonistThe predicted DBL oncogene product defines a distinct class of transforming proteinsPrognostic molecular markers in early breast cancerTyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinasesHER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cellsInhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.G Protein-Coupled Receptor Signaling in Stem Cells and CancerErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptorHER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancerThe HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitorComparative methodological analysis of erbB-2/HER-2 gene dosage, chromosomal copy number and protein overexpression in breast carcinoma tissues for diagnostic useSignaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometryCorrelation of the structure of the transmembrane domain of the neu oncogene-encoded p185 protein with its functionTransformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2Multiple Bacteriophage Selection Strategies for Improved Affinity of a Peptide Targeting ERBB2MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancerExpression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potencyDominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/NeuErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancerThe relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH3T3 cellsSnail induction is an early response to Gli1 that determines the efficiency of epithelial transformationc-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
P2860
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P2860
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@en
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@nl
type
label
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@en
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@nl
prefLabel
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@en
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@nl
P2093
P356
P1433
P1476
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells.
@en
P2093
P304
P356
10.1126/SCIENCE.2885917
P407
P577
1987-07-01T00:00:00Z