Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins
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Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cellsDown-regulation of expression and function of nucleoside diphosphate kinase in insulin-secreting beta-cells under in vitro conditions of glucolipotoxicityYES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cellsInosine monophosphate dehydrogenase: A molecular switch integrating pleiotropic GTP-dependent beta-cell functions.Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.Small G proteins in islet beta-cell function.Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.Regulatory roles for small G proteins in the pancreatic beta-cell: lessons from models of impaired insulin secretion.EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein PalmitoylationEmerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.Rosuvastatin and atorvastatin: comparative effects on glucose metabolism in non-diabetic patients with dyslipidaemia.In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure.Bridging the gap between protein carboxyl methylation and phospholipid methylation to understand glucose-stimulated insulin secretion from the pancreatic beta cell.Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin.Diabetogenic effect of statins: a double-edged sword?Do statins cause diabetes?The diabetogenic action of statins - mechanisms and clinical implications.Statin use and the risk of developing diabetes: a network meta-analysis.Biologically active lipids promote trafficking and membrane association of Rac1 in insulin-secreting INS 832/13 cells.Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells.Novel roles for the rho subfamily of GTP-binding proteins in succinate-induced insulin secretion from betaTC3 cells: further evidence in support of the succinate mechanism of insulin release.The basal subcellular distribution of beta-adrenergic receptor kinase is independent of G-protein beta gamma subunits.Characterization of prenylcysteine methyltransferase in insulin-secreting cellsAtorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress.Activation of alpha-2-adrenoceptors results in an increase in F-actin formation in HIT-T15 pancreatic B-cells.Store-activated Ca2+ inflow in Xenopus laevis oocytes: inhibition by primaquine and evaluation of the role of membrane fusion.A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells.Nifedipine prevents etoposide-induced caspase-3 activation, prenyl transferase degradation and loss in cell viability in pancreatic β-cells.Nerve growth factor-specific regulation of protein methylation during neuronal differentiation of PC12 cells.Stimulation by prostaglandin E2 of a high-affinity GTPase in the secretory granules of normal rat and human pancreatic islets.Characterization of prenylated protein methyltransferase in Leishmania.Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells.Role of G-proteins in islet function in health and diabetes.GGPPS-mediated Rab27A geranylgeranylation regulates β cell dysfunction during type 2 diabetes development by affecting insulin granule docked pool formation.
P2860
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P2860
Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Modulation of insulin secretio ...... ations of GTP-binding proteins
@en
Modulation of insulin secretio ...... ations of GTP-binding proteins
@nl
type
label
Modulation of insulin secretio ...... ations of GTP-binding proteins
@en
Modulation of insulin secretio ...... ations of GTP-binding proteins
@nl
prefLabel
Modulation of insulin secretio ...... ations of GTP-binding proteins
@en
Modulation of insulin secretio ...... ations of GTP-binding proteins
@nl
P2093
P2860
P356
P1433
P1476
Modulation of insulin secretio ...... ations of GTP-binding proteins
@en
P2093
P2860
P356
10.1042/BJ2950031
P407
P478
295 ( Pt 1)
P577
1993-10-01T00:00:00Z