Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.
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Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and AktPrdx1 inhibits tumorigenesis via regulating PTEN/AKT activity(1)H NMR studies distinguish the water soluble metabolomic profiles of untransformed and RAS-transformed cells14-3-3gamma induces oncogenic transformation by stimulating MAP kinase and PI3K signaling.FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells.Palmitoylation of oncogenic NRAS is essential for leukemogenesis.Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterationsRAS Interaction with PI3K: More Than Just Another Effector PathwayEvidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphateCompartmentalized Ras proteins transform NIH 3T3 cells with different efficienciesCharacterization of KRAS rearrangements in metastatic prostate cancer.Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.Human Dynactin-Associated Protein Transforms NIH3T3 Cells to Generate Highly Vascularized Tumors with Weak Cell-Cell Interaction.TRAIL induces apoptosis in oral squamous carcinoma cells--a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5.Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.TGFBR1*6A enhances the migration and invasion of MCF-7 breast cancer cells through RhoA activation.Emerging Raf inhibitors.Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool.The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection.Chemistry and biology of the compounds that modulate cell migration.Collagen I regulates the self-renewal of mouse embryonic stem cells through α2β1 integrin- and DDR1-dependent Bmi-1.Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansionGILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling.Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome.A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors.Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.
P2860
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P2860
Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@en
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@nl
type
label
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@en
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@nl
prefLabel
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@en
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@nl
P2093
P2860
P356
P1476
Transformation potential of Ra ...... inositol 3-kinase but not ERK.
@en
P2093
Kun-Liang Guan
Tianqing Zhu
Weiquan Li
P2860
P304
37398-37406
P356
10.1074/JBC.M405730200
P407
P577
2004-06-21T00:00:00Z