Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate - Wikidata - wikimedia - TriplyDB

Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

http://www.wikidata.org/entity/Q34719423

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Akt and mTOR in B Cell Activation and Differentiation PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12 Targeting the intragraft microenvironment and the development of chronic allograft rejection Regulation of mTORC1 by PI3K signaling Phosphoinositides: tiny lipids with giant impact on cell regulation From Learning to Memory: What Flies Can Tell Us about Intellectual Disability Treatment The TORC2 component, Sin1, controls migration of anterior mesendoderm during zebrafish gastrulation PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR 17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.PKCβII acts downstream of chemoattractant receptors and mTORC2 to regulate cAMP production and myosin II activity in neutrophils Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells Identification of mTORC2 as a necessary component of HRG/ErbB2-dependent cellular transformation Mis-regulation of mammalian target of rapamycin (mTOR) complexes induced by albuminuria in proximal tubules.Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion Intersection of mTOR and STAT signaling in immunity Hydronephrotic urine in the obstructed kidney promotes urothelial carcinoma cell proliferation, migration, invasion through the activation of mTORC2-AKT and ERK signaling pathways.Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.Molecular and Functional Characterization of Three Different Postzygotic Mutations in PIK3CA-Related Overgrowth Spectrum (PROS) Patients: Effects on PI3K/AKT/mTOR Signaling and Sensitivity to PIK3 Inhibitors.Review series: TOR kinase complexes and cell migration.Mechanical regulation of glycogen synthase kinase 3β (GSK3β) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein.Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo.mTOR complex 2 signaling and functions Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses LST8 regulates cell growth via target-of-rapamycin complex 2 (TORC2).Alternative Activation Mechanisms of Protein Kinase B Trigger Distinct Downstream Signaling Responses.Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+ T Cell Responses during Acute Viral and Intracellular Bacterial Infections Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.De novo lipogenesis in the liver in health and disease: more than just a shunting yard for glucose Capillary Isoelectric Focusing of Akt Isoforms Identifies Highly Dynamic Phosphorylation in Neuronal Cells and Brain Tissue mTORC2 mediates CXCL12-induced angiogenesis Targeting the Mammalian Target of Rapamycin (mTOR) in Cancer Therapy: Lessons from Past and Future Perspectives Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell lines

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Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

http://www.wikidata.org/entity/Q34719423

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@ast

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@en

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@nl

type

label

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@ast

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@en

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@nl

prefLabel

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@ast

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@en

Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@nl

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JBC.M110.195016

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Journal of Biological Chemistry

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Evidence for direct activation ...... ylinositol 3,4,5-trisphosphate

@en

P2093

Bing Su

http://www.w3.org/2001/XMLSchema#string

Dianqing Wu

http://www.w3.org/2001/XMLSchema#string

Jiyong Wang

http://www.w3.org/2001/XMLSchema#string

Xiaoqing Gan

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Identification of Protor as a novel Rictor-binding component of mTOR complex-2

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

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10998-11002

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scholarly article

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10.1074/JBC.M110.195016

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13

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286

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21310961

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3064154

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