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mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptideMammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitiveTwo TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth controlTIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificityThe mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase CQuantitation of changes in protein phosphorylation: a simple method based on stable isotope labeling and mass spectrometryCalcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytesTor signalling in bugs, brain and brawn.TFEBulous control of traffic by mTOR.mTOR complex 2 signaling and functionsRegulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2)Protein kinase Cζ exhibits constitutive phosphorylation and phosphatidylinositol-3,4,5-triphosphate-independent regulationTOR regulation of AGC kinases in yeast and mammals.What controls TOR?Mammalian TOR signaling to the AGC kinases.mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1JNK is involved in signal integration during costimulation of T lymphocytes.Mammalian target of rapamycin complex 2 modulates αβTCR processing and surface expression during thymocyte development.Restoration of Normal Cerebral Oxygen Consumption with Rapamycin Treatment in a Rat Model of Autism-Tuberous Sclerosis.Effects of rapamycin on cerebral oxygen supply and consumption during reperfusion after cerebral ischemia.mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes.Akt activation improves microregional oxygen supply/consumption balance after cerebral ischemia-reperfusion.Phosphatase Targets in TOR SignalingmTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvationTargeting mTOR and Metabolism in Cancer: Lessons and InnovationsInhibition of p70 ribosomal S6 kinase 1 (S6K1) by PF-4708671 decreased infarct size in early cerebral ischemia-reperfusion with decreased BBB permeabilityThe young and the restless: Isolating the dynamic mammalian preribosomesAmplifying mTORC2 signals through AMPK during energetic stress
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Estela Jacinto
@ast
Estela Jacinto
@en
Estela Jacinto
@es
Estela Jacinto
@nl
Estela Jacinto
@sl
type
label
Estela Jacinto
@ast
Estela Jacinto
@en
Estela Jacinto
@es
Estela Jacinto
@nl
Estela Jacinto
@sl
prefLabel
Estela Jacinto
@ast
Estela Jacinto
@en
Estela Jacinto
@es
Estela Jacinto
@nl
Estela Jacinto
@sl
P106
P21
P31
P496
0000-0001-7118-1759