DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan.
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The study of psychiatric disease genes and drugs in zebrafishMissense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in miceEvaluating historical candidate genes for schizophreniaPAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence.Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory AcquisitionDifferent Paths to Core Pathology: The Equifinal Model of the Schizophrenia SyndromeMisassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics.Disrupted-in-Schizophrenia-1 is essential for normal hypothalamic-pituitary-interrenal (HPI) axis function.Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia.Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness.Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function.Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro.The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions.Recent genetic findings in schizophrenia and their therapeutic relevanceTranslating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies.Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics.DISC1 causes associative memory and neurodevelopmental defects in fruit flies.Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapsesAbnormal wake/sleep pattern in a novel gain-of-function model of DISC1Prospects for Modeling Abnormal Neuronal Function in Schizophrenia Using Human Induced Pluripotent Stem Cells.The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484.Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development.Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways.Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 × DISC1.Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism.The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET studyConvergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression
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DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan.
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DISC1 as a genetic risk factor ...... illness: response to Sullivan.
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DISC1 as a genetic risk factor ...... illness: response to Sullivan.
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DISC1 as a genetic risk factor ...... illness: response to Sullivan.
@en
DISC1 as a genetic risk factor ...... illness: response to Sullivan.
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DISC1 as a genetic risk factor ...... illness: response to Sullivan.
@en
DISC1 as a genetic risk factor ...... illness: response to Sullivan.
@nl
P2093
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DISC1 as a genetic risk factor ...... illness: response to Sullivan.
@en
P2093
D H Blackwood
D J Porteous
D St Clair
J K Millar
P A Thomson
S J Clapcote
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P2888
P304
P356
10.1038/MP.2013.160
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P50
P577
2014-02-01T00:00:00Z