Kinetics of vitamin D3 metabolism by cytochrome P450scc (CYP11A1) in phospholipid vesicles and cyclodextrin.
about
Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes.Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity.Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activityLumisterol is metabolized by CYP11A1: discovery of a new pathwayProduction of 22-hydroxy metabolites of vitamin d3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cellsMetabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.A Proposed Molecular Mechanism of High-Dose Vitamin D3 Supplementation in Prevention and Treatment of Preeclampsia.Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives.Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytesHydroxylation of 20-hydroxyvitamin D3 by human CYP3A4.Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3.In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.On the role of classical and novel forms of vitamin D in melanoma progression and management.Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity.Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity.Metabolism of vitamin d2 to 17,20,24-trihydroxyvitamin d2 by cytochrome p450scc (CYP11A1).20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytesDesign, synthesis, and biological action of 20R-hydroxyvitamin D3.Metabolism of cholesterol, vitamin D3 and 20-hydroxyvitamin D3 incorporated into phospholipid vesicles by human CYP27A1Expression of human CYP27B1 in Escherichia coli and characterization in phospholipid vesicles.Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites.Properties of purified CYP2R1 in a reconstituted membrane environment and its 25-hydroxylation of 20-hydroxyvitamin D3.Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ.
P2860
Q28570398-0832F46E-B450-41B5-A73C-FBE985E5C8F1Q33471485-1BD520D3-1E08-490E-84B0-4A2A5C16898AQ33548669-DB56EAF0-548C-4E88-A33F-B2280539D4EBQ33588771-C4110E8F-D89F-4AF0-BCD5-C03AC9438E21Q34127897-5C1B3865-6D6F-41DD-A44B-A90452C388F0Q34615029-E8FDE3CF-94A0-4343-BC72-F0F5A6D8F48AQ35187882-AD0C71E8-5B0E-49BA-A988-AC15D7D42D81Q35236381-9271CA33-6A67-4AB5-8D66-6CF848D992B1Q35776648-5DF8C3C8-349E-4798-A140-9BE288159241Q35813964-4C27F594-D56A-422E-91F4-61D2202A82E1Q36185515-9EC9EA83-9106-4AFE-8F6B-4B80476E7A0BQ36460824-3B3B470C-30B8-4FA2-800E-0A9BA3933D94Q36767930-1536FF1F-50E5-4489-8527-A4358D58E397Q36776598-CFC6BF4B-48FA-45F5-83F3-1DD47DB6374FQ37021137-27CE608A-6107-441F-B611-AB626198E6F5Q37719172-2A5A4C7F-C944-4A70-BD85-B88374517DA8Q38662850-C6BEE484-7325-4B04-A589-FA385498A8CAQ39694085-AD69BA33-3043-4E52-9B28-3DF2CD4F5374Q41506881-45778B9A-9276-4609-BB1D-B680ACA28FF3Q41896697-4A9F65EA-5D48-4753-AEF8-FDD648A9D7C1Q41968504-796D8163-E904-405D-BC69-1E384188A5A6Q42535614-B8E7A52C-A026-4CC8-9A53-97DF247F40ADQ42582010-4BE2AAF4-B63C-41B2-83EF-15C94D0D5DCBQ44646286-97AD72CB-D185-4687-9577-945A900BB8EAQ48218051-D009C641-F02F-43C2-B97D-AEF132AABD47Q49923288-0E7A755C-22DA-42C8-BCCB-AC9AE70728B3Q50885385-B4B01D2E-2AA5-498A-B237-05A1B6ABA846Q51442356-75ACA875-7FE6-481E-9026-3697C745170E
P2860
Kinetics of vitamin D3 metabolism by cytochrome P450scc (CYP11A1) in phospholipid vesicles and cyclodextrin.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Kinetics of vitamin D3 metabol ...... pid vesicles and cyclodextrin.
@en
Kinetics of vitamin D3 metabolism by cytochrome P450scc
@nl
type
label
Kinetics of vitamin D3 metabol ...... pid vesicles and cyclodextrin.
@en
Kinetics of vitamin D3 metabolism by cytochrome P450scc
@nl
prefLabel
Kinetics of vitamin D3 metabol ...... pid vesicles and cyclodextrin.
@en
Kinetics of vitamin D3 metabolism by cytochrome P450scc
@nl
P2860
P1476
Kinetics of vitamin D3 metabol ...... ipid vesicles and cyclodextrin
@en
P2093
Minh N Nguyen
P2860
P304
P356
10.1016/J.BIOCEL.2008.05.006
P577
2008-05-20T00:00:00Z