Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
about
Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With ImmunotherapyUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingCD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axisA single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.T-cell regulation by CD28 and CTLA-4.NKG2D receptor regulates human effector T-cell cytokine production.Gene expression profiling-based identification of CD28 and PI3K as new biomarkers for chronic graft-versus-host disease.Lymphocyte calcium signaling from membrane to nucleus.CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production.Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes.Signalling molecules and cytokine production in T cells of multiple myeloma-increased abnormalities with advancing stage.Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.Pharmacologic profiling of transcriptional targets deciphers promoter logic.Glycogen Synthase Kinase 3 Inactivation Compensates for the Lack of CD28 in the Priming of CD8+ Cytotoxic T-Cells: Implications for anti-PD-1 Immunotherapy.Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins.Defects in regulatory T cells due to CD28 deficiency induce a qualitative change of allogeneic immune response in chronic graft-versus-host disease.CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.
P2860
Q26796309-3ABA7B30-B71D-4812-B46B-10815EAC8210Q28189055-2B684B76-3C39-4644-84A5-4CF50430B671Q28295777-35C4014F-9997-4D85-A4E5-77F057D5B061Q28610409-5A8793B1-474B-4C03-9482-EFDDE5E1509CQ30009490-9404D5EB-C3F0-4628-B1EB-871BEDA1F2D3Q33932904-B57D3295-539A-427A-BE0B-041DCFDE25DBQ34572202-242081B3-F69B-4078-908B-CFAC227F6B85Q35067621-17E6710B-1CA8-4A42-B852-ED802A56C396Q35601779-2A2B0FD2-A215-4E0A-8B02-8320E3BACE27Q36343541-6626C67B-CAC9-44F0-A735-A843D2EED928Q41969372-6C85F822-C0D8-4071-B52A-F477860FA200Q42287222-04E1138E-06E8-4A3B-8EEB-C3D2B79D32FBQ42944831-8AEB1B86-4645-430E-B560-CEAD7052C7CFQ44235062-B2179CA8-D277-4BCE-BAA3-DA6AC142511DQ44724638-EF964EB8-00D4-488D-A125-BAF8B45D9608Q46348775-7EFED41F-F6AA-4514-A0F1-67DC30E2810FQ46619121-56EB316E-F7C6-43C2-8813-955212F0D0C7Q47223979-AF291D9E-9C15-437E-8D5A-7FDD7C8F3E29Q51280484-B10968C9-99B1-43B0-866A-DF635334AA39Q52954957-545BD783-9752-451D-8F06-EE1F4D12AFDAQ54408164-1820F452-BB66-4A56-B176-36C71B454F3F
P2860
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@en
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@nl
type
label
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@en
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@nl
prefLabel
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@en
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@nl
P2093
P2860
P356
P1476
Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation.
@en
P2093
A Matsumoto
R Watanabe
P2860
P304
P356
10.1074/JBC.M005051200
P407
P577
2000-12-11T00:00:00Z