Zn2+ and H+ are coactivators of acid-sensing ion channels. - Wikidata - wikimedia - TriplyDB

Zn2+ and H+ are coactivators of acid-sensing ion channels.

Zn2+ and H+ are coactivators of acid-sensing ion channels.

http://www.wikidata.org/entity/Q43678707

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Proton-binding sites of acid-sensing ion channel 1 The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1 Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as Metalloproteins Structure and activity of the acid-sensing ion channels Acid-sensing ionic channels in the rat vestibular endorgans and ganglia Selective regulation of acid-sensing ion channel 1 by serine proteases Stomatin modulates gating of acid-sensing ion channels Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1 Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing The Concise Guide to PHARMACOLOGY 2013/14: ion channels A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.Acid-sensing ion channels in mouse olfactory bulb M/T neurons.Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a The contact region between three domains of the extracellular loop of ASIC1a is critical for channel function.Acid-sensing ion channels in acidosis-induced injury of human brain neurons Acid-sensing ion channels (ASICs): therapeutic targets for neurological diseases and their regulation High-density expression of Ca2+-permeable ASIC1a channels in NG2 glia of rat hippocampus.Molecular determinants of proton modulation of glycine receptors.ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents.Zebrafish acid-sensing ion channel (ASIC) 4, characterization of homo- and heteromeric channels, and identification of regions important for activation by H+.Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death Expression and activity of acid-sensing ion channels in the mouse anterior pituitary.Cysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition.Inhibition of human acid-sensing ion channel 1b by zinc The neurobiology of zinc in health and disease.Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a.Acid-Sensing Ion Channels Expression, Identity and Role in the Excitability of the Cochlear Afferent Neurons Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes.Acid-sensing ion channels (ASICs) in mouse skeletal muscle afferents are heteromers composed of ASIC1a, ASIC2, and ASIC3 subunits.Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel Acid-sensing ion channels are expressed in the ventrolateral medulla and contribute to central chemoreception.A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons.Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a.

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P2860

Zn2+ and H+ are coactivators of acid-sensing ion channels.

http://www.wikidata.org/entity/Q43678707

description

2001 nî lūn-bûn

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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2001年學術文章

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name

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@en

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@nl

type

label

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@en

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@nl

prefLabel

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@en

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@nl

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Journal of Biological Chemistry

P1476

Zn2+ and H+ are coactivators of acid-sensing ion channels.

@en

P2093

Baron A

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Champigny G

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Lazdunski M

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Lingueglia E

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Schaefer L

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P2860

A new member of acid-sensing ion channels from pituitary gland

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Cloning and expression of a novel human brain Na+ channel

Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel

BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels

A proton-gated cation channel involved in acid-sensing

Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons

Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+

The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties

TASK-3, a new member of the tandem pore K(+) channel family

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10.1074/JBC.M105208200

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38

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276

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11457851

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