Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
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Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosisCentriole assembly and the role of Mps1: defensible or dispensable?The serine/threonine kinase Nek6 is required for cell cycle progression through mitosisDishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1.ZW10 links mitotic checkpoint signaling to the structural kinetochore.Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balanceHuman Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplicationMPS1-dependent mitotic BLM phosphorylation is important for chromosome stabilityHuman Mps1 protein kinase is required for centrosome duplication and normal mitotic progressionA new view of the spindle checkpointMicrotubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signalingHuman MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresMG-132, an inhibitor of proteasomes and calpains, induced inhibition of oocyte maturation and aneuploidy in mouse oocytesFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisChromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomesKinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochoresThe multiple roles of mps1 in Drosophila female meiosisHypoxia transiently sequesters mps1 and polo to collagenase-sensitive filaments in Drosophila prometaphase oocytesStructural and mechanistic insights into Mps1 kinase activationSmall-molecule kinase inhibitors provide insight into Mps1 cell cycle functionMad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.Emi1 is required for cytostatic factor arrest in vertebrate eggsCentromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)atedEmi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteinsIn-silico modeling of the mitotic spindle assembly checkpointChemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosisQuantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screeningStructural and functional characterization of the protein kinase Mps1 in Arabidopsis thalianaIdentification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosisIdentification of genes periodically expressed in the human cell cycle and their expression in tumorsA Centromere-Signaling Network Underlies the Coordination among Mitotic EventsConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores.Kinetochore localization of spindle checkpoint proteins: who controls whom?Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex.Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.Mps1 promotes rapid centromere accumulation of Aurora B.
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P2860
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
@en
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
@nl
type
label
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
@en
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
@nl
prefLabel
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
@en
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
@nl
P2093
P50
P1433
P1476
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint
@en
P2093
J A Kahana
L Magnaghi-Jaulin
S Vigneron
P356
10.1016/S0092-8674(01)00410-X
P407
P577
2001-07-01T00:00:00Z