Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).
about
Structural reorganization of the interleukin-7 signaling complexmTOR and cancer therapyThe physiology and pathophysiology of rapamycin resistance: implications for cancerAltered thymic function during interferon therapy in HCV-infected patientsAberrant expression of functional BAFF-system receptors by malignant B-cell precursors impacts leukemia cell survivalReversal of tumor immune inhibition using a chimeric cytokine receptor.zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia.Interleukin-7 and Immunosenescence.Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.IL-7 in human health and disease.Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progressionRapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling.Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responsesEffects of STI571 and p27 gene clone on proliferation and apoptosis of K562 cells.Occurrence of leukaemia following gene therapy of X-linked SCID.Interferon-α inhibits CD4 T cell responses to interleukin-7 and interleukin-2 and selectively interferes with Akt signaling.The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and Homeostasis.RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma.Stimulated plasmacytoid dendritic cells impair human T-cell developmentExpression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection.The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells.Therapeutic potential of target of rapamycin inhibitors.Mammalian target of rapamycin (mTOR) inhibition in chronic lymphocytic B-cell leukemia: a new therapeutic option.Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis?IL-7 promotes T cell proliferation through destabilization of p27Kip1.Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing γδ cells.Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells.Interlinking interleukin-7.microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemiaGlucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.Research using Mesenchymal Stem/Stromal Cells: quality metric towards developing a reference material.Aberrant signaling in T-cell acute lymphoblastic leukemia: biological and therapeutic implications.An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.It's T-ALL about Notch.Tumor immune therapy: lessons from infection and implications for cancer - can IL-7 help overcome immune inhibitory networks?Genotoxicity of retroviral hematopoietic stem cell gene therapy.Cell cycle regulatory molecular profiles of pediatric T-cell lymphoblastic leukemia and lymphoma.Therapeutic potential of Notch inhibition in T-cell acute lymphoblastic leukemia: rationale, caveats and promises.Structural insights into the common γ-chain family of cytokines and receptors from the interleukin-7 pathway.Interleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia.
P2860
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P2860
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Interleukin-7 promotes surviva ...... dependent kinase inhibitor p27
@nl
Interleukin-7 promotes surviva ...... nt kinase inhibitor p27(kip1).
@en
type
label
Interleukin-7 promotes surviva ...... dependent kinase inhibitor p27
@nl
Interleukin-7 promotes surviva ...... nt kinase inhibitor p27(kip1).
@en
prefLabel
Interleukin-7 promotes surviva ...... dependent kinase inhibitor p27
@nl
Interleukin-7 promotes surviva ...... nt kinase inhibitor p27(kip1).
@en
P2093
P356
P1433
P1476
Interleukin-7 promotes surviva ...... nt kinase inhibitor p27(kip1).
@en
P2093
Boussiotis VA
Cardoso AA
P304
P356
10.1182/BLOOD.V98.5.1524
P407
P577
2001-09-01T00:00:00Z