Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.
about
GADD45 induction of a G2/M cell cycle checkpointEffects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator geneThe human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1Interaction of p53 with the human Rad51 proteinA human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonucleaseIdentification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint geneA human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control geneHRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control geneProapoptotic p53-interacting protein 53BP2 is induced by UV irradiation but suppressed by p53p53 is linked directly to homologous recombination processes via RAD51/RecA protein interactionDetection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridizationRACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutationUnbalanced replication as a major source of genetic instability in cancer cellsThe first 30 years of p53: growing ever more complexMechanisms of G2 arrest in response to overexpression of p53Homologous Recombination and Its Role in CarcinogenesisPossible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fieldsp19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathwaysLinks between mutant p53 and genomic instabilityCrystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstromsp53 in the DNA-Damage-Repair ProcessExit from arsenite-induced mitotic arrest is p53 dependentNF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1p53 and Bax: putative death factors in taste cell turnoverPersistent nicotine treatment potentiates amplification of the dihydrofolate reductase gene in rat lung epithelial cells as a consequence of Ras activationMapping of the p53 and mdm-2 interaction domainsAccumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathwayAmplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaksRadiation effects on DNA synthesis in a defined chromosomal replicon.Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.The rate of folate receptor alpha (FR alpha) synthesis in folate depleted CHL cells is regulated by a translational mechanism sensitive to media folate levels, while stable overexpression of its mRNA is mediated by gene amplification and an increasePolycyclic aromatic hydrocarbon carcinogens increase ubiquitination of p21 protein after the stabilization of p53 and the expression of p21.Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage.p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescenceCell cycle control, checkpoint mechanisms, and genotoxic stress.Insights into cancer from transgenic mouse models.Activation of caspases and p53 by bovine herpesvirus 1 infection results in programmed cell death and efficient virus release.Mutant p53 gain-of-function in cancer.Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators.
P2860
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P2860
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles.
@en
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles.
@nl
type
label
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles.
@en
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles.
@nl
prefLabel
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles.
@en
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles.
@nl
P2093
P1433
P1476
Wild-type p53 restores cell cy ...... cells with mutant p53 alleles
@en
P2093
P304
P356
10.1016/0092-8674(92)90244-7
P407
P50
P577
1992-09-01T00:00:00Z