The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation.
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Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cellsPhosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinaseDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsXLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligationEssential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorBeyond DNA repair: DNA-PK function in cancerDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayAutophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.DNA-PK autophosphorylation facilitates Artemis endonuclease activityThe response to and repair of RAG-mediated DNA double-strand breaksActivation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6.PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinaseAutophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks.Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and developmentCoincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining.Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damagePhosphatases in the cellular response to DNA damage.A structural model for regulation of NHEJ by DNA-PKcs autophosphorylationScanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after γ-irradiation and bleomycin treatment.Choosing the right path: does DNA-PK help make the decision?Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies.The role of the non-homologous end-joining pathway in lymphocyte development.The DNA-dependent protein kinase: the director at the end.XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV StimulationDNA-PKcs function regulated specifically by protein phosphatase 5LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repairNon-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks.Increased Artemis levels confer radioresistance to both high and low LET radiation exposures.The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cellsHTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinaseGenistein sensitizes sarcoma cells in vitro and in vivo by enhancing apoptosis and by inhibiting DSB repair pathwaysInhibiting the DNA damage response as a therapeutic manoeuvre in cancer.DNA double strand break repair via non-homologous end-joining.Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing
P2860
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P2860
The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation.
description
2002 nî lūn-bûn
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2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
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2002年学术文章
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2002年學術文章
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name
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@en
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@nl
type
label
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@en
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@nl
prefLabel
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@en
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@nl
P2093
P356
P1433
P1476
The DNA-dependent protein kina ...... disrupted by phosphorylation.
@en
P2093
David Cramb
David P Bazett-Jones
Dennis Merkle
Greg B G Moorhead
Pauline Douglas
Susan P Lees-Miller
Zoya Leonenko
P304
12706-12714
P356
10.1021/BI0263558
P407
P577
2002-10-01T00:00:00Z