A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor.
about
Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liverSelective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels.Biomolecular chemistry of isopropyl fibratesEffect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome.Carboxylesterases are uniquely expressed among tissues and regulated by nuclear hormone receptors in the mouse.Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis.Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor alpha-independent mechanism.PPAR and liver injury in HIV-infected patients.Orphan nuclear receptors as targets for drug development.Targeting liver X receptors in human health: deadlock or promising trail?Early investigational drugs targeting PPAR-α for the treatment of metabolic disease.Therapeutic applications of the versatile fatty acid mimetic WY14643.Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease.Chronic treatment with fibrates elevates superoxide dismutase in adult mouse brain microvessels.Liver X receptor activation inhibits SGLT2-mediated glucose transport in human renal proximal tubular cells.Activation of liver X receptor inhibits OCT2-mediated organic cation transport in renal proximal tubular cells.
P2860
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P2860
A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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name
A chemical switch regulates fi ...... pha ) versus liver X receptor.
@en
A chemical switch regulates fi ...... rator-activated receptor alpha
@nl
type
label
A chemical switch regulates fi ...... pha ) versus liver X receptor.
@en
A chemical switch regulates fi ...... rator-activated receptor alpha
@nl
prefLabel
A chemical switch regulates fi ...... pha ) versus liver X receptor.
@en
A chemical switch regulates fi ...... rator-activated receptor alpha
@nl
P2093
P2860
P356
P1476
A chemical switch regulates fi ...... lpha ) versus liver X receptor
@en
P2093
Anton Kiefer
Chahrzad Montrose
Denis McCann
Guoqing Cao
Jeff McCowan
Jeffrey Thomas
Kelli S Bramlett
Kuo-Long Yu
Laura F Michael
Patricia Foxworthy
P2860
P304
P356
10.1074/JBC.M209629200
P407
P50
P577
2002-11-18T00:00:00Z