Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
about
Chk2 activation dependence on Nbs1 after DNA damageTrans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchangePhosphorylation of HuR by Chk2 regulates SIRT1 expressionThe stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathwayChk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repairRegulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cellsPolo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbodyHuman MMS21/NSE2 is a SUMO ligase required for DNA repairFunctional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppressionRNA interference inhibition of Mus81 reduces mitotic recombination in human cellsInvolvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damageIrofulven induces replication-dependent CHK2 activation related to p53 statusStudy design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE studyMutation analysis of the CHK2 gene in breast carcinoma and other cancersMammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathwaysTargeted disruption of NBS1 reveals its roles in mouse development and DNA repair.Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domainMDC1 is coupled to activated CHK2 in mammalian DNA damage response pathwaysChecking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressorNFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage responseNFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathwaysEDD mediates DNA damage-induced activation of CHK2Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphataseSuppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell CycleA mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpointChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageXenopus Cds1 is regulated by DNA-dependent protein kinase and ATR during the cell cycle checkpoint response to double-stranded DNA endsATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention.Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex.Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.Rad9A is required for G2 decatenation checkpoint and to prevent endoreduplication in response to topoisomerase II inhibitionHepatitis C virus NS5B protein delays s phase progression in human hepatocyte-derived cells by relocalizing cyclin-dependent kinase 2-interacting protein (CINP).Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast.MAPK signaling mediates sinomenine hydrochloride-induced human breast cancer cell death via both reactive oxygen species-dependent and -independent pathways: an in vitro and in vivo study.Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response.Phosphatases in the cellular response to DNA damage.Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo.
P2860
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P2860
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@en
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@nl
type
label
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@en
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@nl
prefLabel
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@en
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@nl
P2093
P356
P1433
P1476
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.
@en
P2093
P2888
P304
P356
10.1038/35036406
P577
2000-10-01T00:00:00Z