5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms.
about
Metabolic actions of metformin in the heart can occur by AMPK-independent mechanismsEnergy Metabolism of the Brain, Including the Cooperation between Astrocytes and Neurons, Especially in the Context of Glycogen MetabolismLuminal fructose inhibits rat intestinal sodium-phosphate cotransporter gene expression and phosphate uptakeEnhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranosideGermline deletion of AMP-activated protein kinase beta subunits reduces bone mass without altering osteoclast differentiation or function.AMPK activation: a therapeutic target for type 2 diabetes?Mechanism of action of compound-13: an α1-selective small molecule activator of AMPKAdiponectin signaling in the liverHepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver.AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseasesMechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.Stimulation of N-linked glycosylation and lipid-linked oligosaccharide synthesis by stress responses in metazoan cells.AMP-activated protein kinase and the regulation of glucose transport.AMP-activated protein kinase signaling in metabolic regulation.Role of AMP-activated protein kinase in healthy and diseased hearts.Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators.Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction.AMPK activators--potential therapeutics for metabolic and other diseases.Targeting AMPK for cardiac protection: opportunities and challenges.AMP-activated protein kinase modulators: a patent review (2006 - 2010).Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes.Myocardial glycogen dynamics: new perspectives on disease mechanisms.Activation of AMPK and its Impact on Exercise Capacity.Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion.AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System.AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase.Does long-term metformin treatment increase cardiac lipoprotein lipase?KATP channel deficiency in mouse FDB causes an impairment of energy metabolism during fatigue.AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside.Naturally occurring R225W mutation of the gene encoding AMP-activated protein kinase (AMPK)gamma(3) results in increased oxidative capacity and glucose uptake in human primary myotubes.AMP kinase activation and glut4 translocation in isolated cardiomyocytesChondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.Glucose 6-phosphate causes translocation of phosphorylase in hepatocytes and inactivates the enzyme synergistically with glucose.AMPK stimulation increases LCFA but not glucose clearance in cardiac muscle in vivo.Cardiac glycogen accumulation after dexamethasone is regulated by AMPK.5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside renders glucose output by the liver of the dog insensitive to a pharmacological increment in insulin.Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice.
P2860
Q22241963-24CADCB2-5260-4664-AAB4-69DBDB005153Q26777075-01BDD39F-17DD-4CB6-A110-A5BE8E1C3E87Q28576695-B6C00480-7DB3-45B4-9B3B-AEB61B0E9DB9Q30406455-AF797840-DCFE-478F-AE31-21A63C0F09EAQ33552875-5DD505D5-CB8D-4E9D-951A-BB32749429C3Q33824564-81A0A6C6-E52A-4137-98CB-7B89B528BF61Q33922223-D41BED87-5E5D-4DA2-A70D-C137F3BE3A43Q34125349-1752FBA3-85BF-418F-84F5-69534D3868FAQ34526978-228E4565-167C-482B-8C24-F9403E57BA30Q35103810-010F0BDB-127E-4EA1-8DDB-B9FDF600AEF4Q35224775-6730CCDA-3951-4B26-A0DA-0B75BF15AF10Q36301403-2E335BEE-E97B-4591-9993-FB020C121D52Q36440729-3D2F9D1D-7C06-4E5E-820B-C7F2ED7FD20CQ36528251-73B4AF84-9763-43CA-B9B2-E0108D8CA691Q36528537-535CC03C-53EE-4874-8005-47D4E13367A0Q36537821-7561F776-05D0-49C0-A5C1-D281D2B66DC1Q36943709-7F7A5081-4340-4E05-ACF1-A01B47BAAD9CQ37271886-6B0256DF-C2C0-4837-841B-DD6AEA711C3BQ37372989-3AD5ECED-ED70-4CD8-A58D-726C153AD37CQ37401943-5C726A84-9636-4F41-AC4B-16529F24AF6DQ37819301-BF24BCDF-DBBC-4765-88CE-E5483F3C101DQ37872742-4D9B62D5-66F1-45D6-BFD7-E29257260087Q38130793-D9081EDD-7B20-4713-BFEA-EDFC326A2751Q38353514-750F9BBB-49FF-425B-A7EA-6DCCA1634412Q38549546-B5A1BB9A-2E24-49B0-BC53-144F3EB7F670Q39133938-04F6A3B4-1807-4793-98D3-DD91F0479020Q39331294-9C60BA5E-3E05-43EB-AC00-9892A57DE817Q40036074-B2071D8F-8B96-4EEE-9E98-F49C46B0F3A7Q41221005-624E97FD-F211-493A-936F-3B70822BD783Q41630359-9460F511-4A9B-4E4E-8222-DACEDE18716EQ42021544-99AB8CB8-1391-45EF-A56C-E9830B5D33F7Q42471559-E83CF0EF-21CC-44C8-AD5E-A86D20497F39Q42472572-C04B07AF-6A09-424B-A5D4-41B4C82C6672Q42783350-DD0FC3B0-7201-4199-AB7B-64EF1D66E353Q43003291-2F333258-8925-4275-95ED-6BFC61E16AF4Q43003369-84C79149-B901-4E46-AC47-275F4107DFE0Q44987296-1A7DC7A8-602D-4272-9CAC-98CE911745C8Q46403678-05C5B61B-CC1E-4279-895C-BF56C8CC10D9Q46620833-1B1B80EA-62B4-4637-9F53-815EB7FFA688Q46728828-23CEF6A3-CCBD-437A-B20A-5737D2139A4A
P2860
5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
5-Aminoimidazole-4-carboxamide ...... ysis by allosteric mechanisms.
@en
5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside
@nl
type
label
5-Aminoimidazole-4-carboxamide ...... ysis by allosteric mechanisms.
@en
5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside
@nl
prefLabel
5-Aminoimidazole-4-carboxamide ...... ysis by allosteric mechanisms.
@en
5-Aminoimidazole-4-carboxamide 1-beta -D-ribofuranoside
@nl
P2093
P2860
P1476
5-Aminoimidazole-4-carboxamide ...... ysis by allosteric mechanisms.
@en
P2093
Hannah L Parsons
Michael F Allard
Richard B Wambolt
Roger W Brownsey
Sarah L Longnus
P2860
P304
P356
10.1152/AJPREGU.00319.2002
P577
2003-04-01T00:00:00Z