Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress.
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Non-cysteine linked MUC1 cytoplasmic dimers are required for Src recruitment and ICAM-1 binding induced cell invasionMembrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cellsInhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPHMUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated MechanismMucins in cancer: function, prognosis and therapyMUC1 Predicts Colorectal Cancer Metastasis: A Systematic Review and Meta-Analysis of Case Controlled StudiesAdenoviral vectors for prodrug activation-based gene therapy for cancerLung cancer vaccinesMUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90Mitochondria-ros crosstalk in the control of cell death and agingMUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cellsO-glycan inhibitors generate aryl-glycans, induce apoptosis and lead to growth inhibition in colorectal cancer cell lines.MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patientsCooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.Current status of mucins in the diagnosis and therapy of cancer.MUC1: a multifaceted oncoprotein with a key role in cancer progression.The cytoplasmic domain of MUC1 induces hyperplasia in the mammary gland and correlates with nuclear accumulation of β-catenin.Ageing and long-term smoking affects KL-6 levels in the lung, induced sputum and plasma.Lenalidomide enhances anti-myeloma cellular immunityIntrinsic mitochondrial membrane potential and associated tumor phenotype are independent of MUC1 over-expression.Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance.Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loopMUC1 oncoprotein suppresses activation of the ARF-MDM2-p53 pathwaymiR-1226 targets expression of the mucin 1 oncoprotein and induces cell death.MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancerFunctional targeting of the MUC1 oncogene in human cancersMUC1 oncoprotein functions in activation of fibroblast growth factor receptor signalingMUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.Helicobacter pylori infection synergizes with three inflammation-related genetic variants in the GWASs to increase risk of gastric cancer in a Chinese population.MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cellsThe effect of MUC1 rs4072037 functional polymorphism on cancer susceptibility: evidence from published studies.MUC1 oncoprotein regulates Bcr-Abl stability and pathogenesis in chronic myelogenous leukemia cellsMUC1 and MUC2 in pancreatic neoplasiaMUC1 alters oncogenic events and transcription in human breast cancer cells.Respiratory Homeostasis and Exploitation of the Immune System for Lung Cancer VaccinesGenetic variants at 1q22 and 10q23 reproducibly associated with gastric cancer susceptibility in a Chinese population
P2860
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P2860
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@en
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@nl
type
label
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@en
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@nl
prefLabel
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@en
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@nl
P2093
P2860
P356
P1476
Human MUC1 carcinoma antigen r ...... response to oxidative stress.
@en
P2093
Donald Kufe
Hiroaki Kuwahara
Yongqing Li
P2860
P304
35458-35464
P356
10.1074/JBC.M301987200
P407
P577
2003-06-25T00:00:00Z