Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation.
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Accumulation of human papillomavirus type 16 E7 protein bypasses G1 arrest induced by serum deprivation and by the cell cycle inhibitor p21The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16.E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expressionHuman papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.Human papillomavirus type 16 E7 maintains elevated levels of the cdc25A tyrosine phosphatase during deregulation of cell cycle arrest.Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways.Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutantAbrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoproteinPerturbation of the p53 response by human papillomavirus type 16 E7.Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activityRole of Cdk1 in DNA damage-induced G1 checkpoint abrogation by the human papillomavirus E7 oncogene.The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoproteinThe p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras.Human papillomavirus E7 induces rereplication in response to DNA damageDifferential activation of target cellular promoters by p53 mutants with impaired apoptotic function.Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability.Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesThe human papillomavirus E7 oncoprotein.Mammalian cells resistant to tumor suppressor genes.Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses.The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1.Hypoxia induces p53 accumulation in the S-phase and accumulation of hypophosphorylated retinoblastoma protein in all cell cycle phases of human melanoma cells.Epstein-Barr virus nuclear antigen 3C regulates cyclin A/p27 complexes and enhances cyclin A-dependent kinase activityLack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product.Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication.
P2860
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P2860
Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
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1994年學術文章
@zh-hant
name
Cells expressing HPV16 E7 cont ...... damage induced p53 activation.
@en
Cells expressing HPV16 E7 cont ...... damage induced p53 activation.
@nl
type
label
Cells expressing HPV16 E7 cont ...... damage induced p53 activation.
@en
Cells expressing HPV16 E7 cont ...... damage induced p53 activation.
@nl
prefLabel
Cells expressing HPV16 E7 cont ...... damage induced p53 activation.
@en
Cells expressing HPV16 E7 cont ...... damage induced p53 activation.
@nl
P2093
P1433
P1476
Cells expressing HPV16 E7 cont ...... damage induced p53 activation
@en
P2093
Hickman ES
Picksley SM
Vousden KH
P304
P407
P577
1994-08-01T00:00:00Z