Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.
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The association of mammalian DREAM complex and HPV16 E7 proteinsFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesThe E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth.The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.Cdc6 contributes to abrogating the G1 checkpoint under hypoxic conditions in HPV E7 expressing cells.Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16.Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes.Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 InfectionE2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expressionInactivation of p16 in human mammary epithelial cells by CpG island methylationDisruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin EHuman papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.Growth suppression of human carcinoma cells by reintroduction of the p300 coactivatorThe E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradationBiology of human papillomaviruses.Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins.Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.Human papillomavirus type 16 E7 maintains elevated levels of the cdc25A tyrosine phosphatase during deregulation of cell cycle arrest.Immortalized keratinocyte lines derived from human embryonic stem cellsInhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein.The E7 open reading frame acts in cis and in trans to mediate differentiation-dependent activities in the human papillomavirus type 16 life cycle.Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAFRepression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways.Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoproteinInitiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activityHuman papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways.Role of Cdk1 in DNA damage-induced G1 checkpoint abrogation by the human papillomavirus E7 oncogene.Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix-induced apoptosispRB plays an essential role in cell cycle arrest induced by DNA damageEnhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1.Induction of tetrasomy by human papillomavirus type 16 E7 protein is independent of pRb binding and disruption of differentiation.Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesE7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte culturesThe papillomavirus E7 proteins.High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.Global effects of human papillomavirus type 18 E6/E7 in an organotypic keratinocyte culture system.The human papillomavirus E7 oncoprotein as a regulator of transcription.Activation of papillomavirus late gene transcription and genome amplification upon differentiation in semisolid medium is coincident with expression of involucrin and transglutaminase but not keratin-10.E7 abolishes raf-induced arrest via mislocalization of p21(Cip1).Direct activation of cyclin-dependent kinase 2 by human papillomavirus E7.
P2860
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P2860
Abrogation of growth arrest signals by human papillomavirus type 16 E7 is mediated by sequences required for transformation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Abrogation of growth arrest si ...... s required for transformation.
@ast
Abrogation of growth arrest si ...... s required for transformation.
@en
type
label
Abrogation of growth arrest si ...... s required for transformation.
@ast
Abrogation of growth arrest si ...... s required for transformation.
@en
prefLabel
Abrogation of growth arrest si ...... s required for transformation.
@ast
Abrogation of growth arrest si ...... s required for transformation.
@en
P2093
P2860
P1433
P1476
Abrogation of growth arrest si ...... es required for transformation
@en
P2093
B G Etscheid
D A Galloway
G W Demers
P2860
P304
P407
P577
1996-10-01T00:00:00Z