Perturbation of the p53 response by human papillomavirus type 16 E7.
about
p53 regulation of G(2) checkpoint is retinoblastoma protein dependentThe human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.The human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16.Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain.Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.Biology of human papillomaviruses.HPV16-E7 expression causes fluorodeoxyuridine-mediated radiosensitization in SW620 human colon cancer cells.Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway.Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways.The Asian-American E6 variant protein of human papillomavirus 16 alone is sufficient to promote immortalization, transformation, and migration of primary human foreskin keratinocytes.Inhibition of radiation-induced apoptosis by dexamethasone in cervical carcinoma cell lines depends upon increased HPV E6/E7.Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis.Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2.E7 abolishes raf-induced arrest via mislocalization of p21(Cip1).Degradation of p53, not telomerase activation, by E6 is required for bypass of crisis and immortalization by human papillomavirus type 16 E6/E7.
P2860
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P2860
Perturbation of the p53 response by human papillomavirus type 16 E7.
description
1997 nî lūn-bûn
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1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Perturbation of the p53 response by human papillomavirus type 16 E7.
@ast
Perturbation of the p53 response by human papillomavirus type 16 E7.
@en
type
label
Perturbation of the p53 response by human papillomavirus type 16 E7.
@ast
Perturbation of the p53 response by human papillomavirus type 16 E7.
@en
prefLabel
Perturbation of the p53 response by human papillomavirus type 16 E7.
@ast
Perturbation of the p53 response by human papillomavirus type 16 E7.
@en
P2093
P2860
P1433
P1476
Perturbation of the p53 response by human papillomavirus type 16 E7
@en
P2093
P2860
P304
P407
P577
1997-05-01T00:00:00Z