T cell recognition of the A2 domain of coagulation factor VIII in hemophilia patients and healthy subjects.
about
T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site.HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P.Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a miceSoy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted factor VIII in hemophilia A mice.Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.PEGylation of a factor VIII-phosphatidylinositol complex: pharmacokinetics and immunogenicity in hemophilia A mice.Why do inhibitors develop? Principles of and factors influencing the risk for inhibitor development in haemophilia.CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice.Progress toward inducing immunologic tolerance to factor VIII.Preclinical models used for immunogenicity prediction of therapeutic proteins.Engineering less immunogenic and antigenic FVIII proteins.Factor VIII inhibitors: Advances in basic and translational science.Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti-factor VIII antibodies in hemophilia A mice.T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.Computer-predicted peptides that mimic discontinuous epitopes on the A2 domain of factor VIII.
P2860
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P2860
T cell recognition of the A2 domain of coagulation factor VIII in hemophilia patients and healthy subjects.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-my
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name
T cell recognition of the A2 d ...... patients and healthy subjects.
@en
T cell recognition of the A2 d ...... patients and healthy subjects.
@nl
type
label
T cell recognition of the A2 d ...... patients and healthy subjects.
@en
T cell recognition of the A2 d ...... patients and healthy subjects.
@nl
prefLabel
T cell recognition of the A2 d ...... patients and healthy subjects.
@en
T cell recognition of the A2 d ...... patients and healthy subjects.
@nl
P2093
P2860
P921
P1476
T cell recognition of the A2 d ...... patients and healthy subjects.
@en
P2093
P2860
P304
P356
10.1111/J.1538-7836.2004.00918.X
P577
2004-11-01T00:00:00Z