Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo.
about
Therapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseasesDeciphering c-MYC-regulated genes in two distinct tissues.Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cellsBID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy responseRecombinant adenovirus IL-24-Bax promotes apoptosis of hepatocellular carcinoma cells in vitro and in vivo.BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues.Finding cancer's weakest link.Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma.Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosisChemotherapy-induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction.Apoptotic signaling by c-MYC.Bcl2 family proteins in carcinogenesis and the treatment of cancer.Apoptosis and oncogenesis: give and take in the BCL-2 family.Deconstructing p53 transcriptional networks in tumor suppression.Unravelling mechanisms of p53-mediated tumour suppression.c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis.Myc: the beauty and the beast.Tumor-Suppressor Functions of the TP53 Pathway.MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib.Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation.Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK.Deconstructing networks of p53-mediated tumor suppression in vivo.
P2860
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P2860
Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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name
Specific requirement for Bax, ...... and tumor suppression in vivo.
@en
Specific requirement for Bax, ...... and tumor suppression in vivo.
@nl
type
label
Specific requirement for Bax, ...... and tumor suppression in vivo.
@en
Specific requirement for Bax, ...... and tumor suppression in vivo.
@nl
prefLabel
Specific requirement for Bax, ...... and tumor suppression in vivo.
@en
Specific requirement for Bax, ...... and tumor suppression in vivo.
@nl
P2093
P2860
P356
P1476
Specific requirement for Bax, ...... and tumor suppression in vivo.
@en
P2093
Fanya Rostker
Gerard I Evan
Lamorna Brown-Swigart
P2860
P304
10890-10895
P356
10.1074/JBC.M513655200
P407
P577
2006-02-07T00:00:00Z