Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
about
The peptide-specific alloreactive human T cell repertoire varies largely between individuals and is not extended in HLA-A*0205--anti-HLA-A*0201 pairings.Alloreactivity: an old puzzle revisited.Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule.Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization.Delineation of antigen contact residues on an MHC class II molecule.On the logic of restrictive recognition of peptide by the T-cell antigen receptor.Alloreactivity across HLA barriers is mediated by both naïve and antigen-experienced T cells.The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma.T cell receptor V beta gene usage in a human alloreactive response. Shared structural features among HLA-B27-specific T cell clonesMajor histocompatibility complex-specific prolongation of murine skin and cardiac allograft survival after in vivo depletion of V beta+ T cellsPeptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signalingA rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells.A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity.A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.The presentation of self-peptides: tolerance and competition.A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell cloneConformational constraints involved in MHC class I restricted antigen presentation.Single-residue changes in class I major histocompatibility complex molecules stimulate responses to self peptidesAllopeptides and the alloimmune response.Alloreactive T cells discriminate among a diverse set of endogenous peptides.Engineered secreted T-cell receptor alpha beta heterodimersSelf peptide requirement for class II major histocompatibility complex allorecognition.Transgenic mice expressing a soluble foreign H-2 class I antigen are tolerant to allogeneic fragments presented by self class I but not to the whole membrane-bound alloantigen.Structure and function of the T cell antigen receptor.CD8+ T cell tolerance and autoimmunity to extra-thymic antigens.Activation of a T cell hybridoma by an alloligand results in differential effects on IL-2 secretion and activation-induced cell death.Alloreactive cytotoxic T-cell function, peptide nonspecific.Peptide dependency of alloreactive CD4+ T cell responses.Integrin-mediated interactions influence the tissue specificity of CD8+ cytolytic T lymphocytes.T cell receptor (TCR) repertoire in alloimmune responses.The contribution of peptides to T cell allorecognition and allograft rejection.The HLA likes and dislikes of allospecific and non-MHC-restricted cytotoxic T lymphocytes.The role of endogenous peptides in the direct pathway of alloreactivity to human MHC class II molecules expressed on CHO cells.Presentation without proteolytic cleavage of endogenous precursors in the MHC class I antigen processing pathway.On the nature of peptides involved in T cell alloreactivity.Recognition by class II alloreactive T cells of processed determinants from human serum proteins.Corecognition of HLA-A1 and HLA-DPw3 by a human CD4+ alloreactive T lymphocyte cloneA bovine class I major histocompatibility complex molecule plus a Theileria parva antigen resembles mouse H-2Kd.Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen-presenting cells in vivo.Brain dead donor kidneys are immunologically active: is intervention justified?
P2860
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P2860
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@en
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@nl
type
label
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@en
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@nl
prefLabel
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@en
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@nl
P356
P1433
P1476
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
@en
P2093
P2888
P304
P356
10.1038/341749A0
P407
P577
1989-10-01T00:00:00Z
P6179
1023076897