Convenient synthesis of N-methylamino acids compatible with Fmoc solid-phase peptide synthesis.
about
Getting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsStructure-activity relationship and metabolic stability studies of backbone cyclization and N-methylation of melanocortin peptidesFacile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays.Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies.Design of novel melanocortin receptor ligands: multiple receptors, complex pharmacology, the challengeSynthesis of chemically modified bioactive peptides: recent advances, challenges and developments for medicinal chemistry.Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides.Peptidomimetics, a synthetic tool of drug discovery.Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues.A convenient approach to synthesizing peptide C-terminal N-alkyl amides.Improvement of drug-like properties of peptides: the somatostatin paradigm.N-methylation of peptides and proteins: an important element for modulating biological functions.Homotyrosine-containing cyanopeptolins 880 and 960 and anabaenopeptins 908 and 915 from Planktothrix agardhii CYA 126/8.N-Methyl scanning mutagenesis generates protease-resistant G protein ligands with improved affinity and selectivityEngineering strategy to improve peptide analogs: from structure-based computational design to tumor homing.N-methylation of isopeptide bond as a strategy to resist deubiquitinases.Easy access to triazolinedione-endcapped peptides for chemical ligation.Total Synthesis of Aurantoside G, an N-β-Glycosylated 3-Oligoenoyltetramic Acid from Theonella swinhoei.Conformational properties of secondary amino acids: replacement of pipecolic acid by N-methyl-l-alanine in efrapeptin C.Synthesis of new dicinnamoyl 4-deoxy quinic acid and methyl ester derivatives and evaluation of the toxicity against the pea aphid Acyrthosiphon pisum.Metabolic stability of peptidomimetics: N-methyl and aza heptapeptide analogs of a PKB/Akt inhibitor.Fmoc Methodology: Cleavage from the Resin and Final Deprotection
P2860
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P2860
Convenient synthesis of N-methylamino acids compatible with Fmoc solid-phase peptide synthesis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@en
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@nl
type
label
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@en
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@nl
prefLabel
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@en
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@nl
P356
P1476
Convenient synthesis of N-meth ...... solid-phase peptide synthesis.
@en
P2093
Eric Biron
Horst Kessler
P304
P356
10.1021/JO050477Z
P407
P577
2005-06-01T00:00:00Z