Chemical modulators of heat shock protein 70 (Hsp70) by sequential, microwave-accelerated reactions on solid phase.
about
HSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.Heat shock protein 70 (hsp70) as an emerging drug target.Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone ComplementThe Chemical Biology of Molecular Chaperones--Implications for Modulation of ProteostasisA screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels.Pharmacological targeting of the Hsp70 chaperone.Hsp70 protein complexes as drug targets.Recent progress in asymmetric Biginelli reaction.Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70).Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probesPharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.Enantioselective organocatalytic Hantzsch synthesis of polyhydroquinolines.Chemical manipulation of hsp70 ATPase activity regulates tau stability.Improved enzymatic syntheses of valuable beta-arylalkyl-beta-amino acid enantiomers.Distribution, introduction pathway, and invasion risk analysis of the North American crayfish Procambarus clarkii (Decapoda: Cambaridae) in southeast BrazilScreening for small molecule modulators of Hsp70 chaperone activity using protein aggregation suppression assays: inhibition of the plasmodial chaperone PfHsp70-1
P2860
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P2860
Chemical modulators of heat shock protein 70 (Hsp70) by sequential, microwave-accelerated reactions on solid phase.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Chemical modulators of heat sh ...... ated reactions on solid phase.
@en
Chemical modulators of heat sh ...... ated reactions on solid phase.
@nl
type
label
Chemical modulators of heat sh ...... ated reactions on solid phase.
@en
Chemical modulators of heat sh ...... ated reactions on solid phase.
@nl
prefLabel
Chemical modulators of heat sh ...... ated reactions on solid phase.
@en
Chemical modulators of heat sh ...... ated reactions on solid phase.
@nl
P2093
P1476
Chemical modulators of heat sh ...... rated reactions on solid phase
@en
P2093
Christopher G Evans
Jason E Gestwicki
John Androsavich
Susanne Wisén
P356
10.1016/J.BMCL.2007.11.027
P407
P50
P577
2007-11-17T00:00:00Z