Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
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The Philadelphia chromosome in leukemogenesisCurrent concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemiaLarge-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma.An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities.Function of Ikaros as a tumor suppressor in B cell acute lymphoblastic leukemiaTranscriptional regulation of the Ikzf1 locus.Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signalsEye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse.Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL.Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.Complementary regulation of early B-lymphoid differentiation by genetic and epigenetic mechanisms.Ikaros fingers on lymphocyte differentiation.Ikaros and leukaemia.Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance.Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.Molecular profiling of gene copy number abnormalities in key regulatory genes in high-risk B-lineage acute lymphoblastic leukemia: frequency and their association with clinicopathological findings in Indian patients.Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma.Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia.Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study.Impact of IKZF1 deletions on long-term outcomes of allo-SCT following imatinib-based chemotherapy in adult Philadelphia chromosome-positive ALL.Changing of IKZF1 genotype during Philadelphia-negative precursor-B acute lymphoblastic leukemia progression: a short clinical report.Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL-negative acute lymphoblastic leukemia.Stage-specific control of early B cell development by the transcription factor Ikaros.High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia.Prognostic significance of IKZF1 deletion in adult B cell acute lymphoblastic leukemia: a meta-analysis.The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia.
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P2860
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
@en
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
@nl
type
label
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
@en
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
@nl
prefLabel
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
@en
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.
@nl
P2093
P2860
P356
P1433
P1476
Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2012.204
P577
2012-07-18T00:00:00Z