Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation. - Wikidata - wikimedia - TriplyDB

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.

http://www.wikidata.org/entity/Q47264458

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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways A MALDI-MSI Approach to the Characterization of Radiation-Induced Lung Injury and Medical Countermeasure Development Impact of Superoxide Dismutase Mimetic AEOL 10150 on the Endothelin System of Fischer 344 Rats AEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent.Hypoxia inducible factor 1alpha signaling in fractionated radiation-induced lung injury: role of oxidative stress and tissue hypoxia.Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.Targeting the Renin-angiotensin system combined with an antioxidant is highly effective in mitigating radiation-induced lung damage.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Radiation mitigating properties of the lignan component in flaxseed Mitigation of Lethal Radiation Syndrome in Mice by Intramuscular Injection of 3D Cultured Adherent Human Placental Stromal Cells.Mitigation of radiation-induced lung injury by genistein and EUK-207.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics Radiation damage to the lung: mitigation by angiotensin-converting enzyme (ACE) inhibitors Clarithromycin Attenuates Radiation-Induced Lung Injury in Mice.Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice.Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung Oxidative stress mediates radiation lung injury by inducing apoptosis.A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy.Short-term treatment with a SOD/catalase mimetic, EUK-207, mitigates pneumonitis and fibrosis after single-dose total-body or whole-thoracic irradiation Subcutaneous administration of bovine superoxide dismutase protects lungs from radiation-induced lung injury.Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 mice Early and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damage Impact of SOD-Mimetic Manganoporphyrins on Spin Trapping of Superoxide and Related Artifacts.Changing the energy of an immune response A combination of pre- and post-exposure ascorbic acid rescues mice from radiation-induced lethal gastrointestinal damage.Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor History and development of radiation-protective agents.Antioxidant therapeutics: Pandora's box.Redox-modulated phenomena and radiation therapy: the central role of superoxide dismutases.Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).Radiation countermeasure agents: an update.Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.Catalytic antioxidant therapy by metallodrugs: lessons from metallocorroles.Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung.Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications.

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P2860

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.

http://www.wikidata.org/entity/Q47264458

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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name

Low molecular weight catalytic ...... s from fractionated radiation.

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Low molecular weight catalytic ...... s from fractionated radiation.

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type

label

Low molecular weight catalytic ...... s from fractionated radiation.

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Low molecular weight catalytic ...... s from fractionated radiation.

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prefLabel

Low molecular weight catalytic ...... s from fractionated radiation.

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Low molecular weight catalytic ...... s from fractionated radiation.

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Free Radical Research

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Low molecular weight catalytic ...... s from fractionated radiation.

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Benjamin Gauter-Fleckenstein

http://www.w3.org/2001/XMLSchema#string

Bradley A Thrasher

http://www.w3.org/2001/XMLSchema#string

Fawzia K Salahuddin

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Ines Batinic-Haberle

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Mark W Dewhirst

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Pavel Yarmolenko

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Zahid N Rabbani

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Zeljko Vujaskovic

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P2860

Reactive oxygen special (ROS), troublemakers between nuclear factor-kB (NF-kB) and c-Jun NH2-terminal kinase (JNK)

Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity

Signal transduction to hypoxia-inducible factor 1

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms.

Signal transduction and cellular radiation responses.

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules.

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

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11

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41

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Mitchell S Anscher

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2007-11-01T00:00:00Z

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17957541

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