Cloning and deletion mutagenesis of the alpha2 delta calcium channel subunit from porcine cerebral cortex. Expression of a soluble form of the protein that retains [3H]gabapentin binding activity.
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Mutation in the auxiliary calcium-channel subunit CACNA2D4 causes autosomal recessive cone dystrophyCACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrityFunctional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsPharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentinThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialThe neurobiology of antiepileptic drugsGabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neuronesBlock by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclaseMutations of calcium channel beta subunit genes in miceAge of quantitative proteomics hits voltage-gated calcium channels.Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin.New Horizons in the development of antiepileptic drugs: Innovative strategies.Domain III regulates N-type (CaV2.2) calcium channel closing kineticsVoltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacologyDifferential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.Neuropathic mechanisms in the pathophysiology of burns pruritus: redefining directions for therapy and research.Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit.Altered expression of the voltage-gated calcium channel subunit α₂δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.Calcium currents are enhanced by α2δ-1 lacking its membrane anchor.Preferential action of gabapentin and pregabalin at P/Q-type voltage-sensitive calcium channels: inhibition of K+-evoked [3H]-norepinephrine release from rat neocortical slices.Dissociation of charge movement from calcium release and calcium current in skeletal myotubes by gabapentin.Effects of gabapentin on anxiety induced by simulated public speaking.entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse.Drugging the undruggable: gabapentin, pregabalin and the calcium channel α2δ subunit.Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain.
P2860
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P2860
Cloning and deletion mutagenesis of the alpha2 delta calcium channel subunit from porcine cerebral cortex. Expression of a soluble form of the protein that retains [3H]gabapentin binding activity.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@en
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@nl
type
label
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@en
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@nl
prefLabel
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@en
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@nl
P2860
P356
P1476
Cloning and deletion mutagenes ...... H]gabapentin binding activity.
@en
P2860
P304
25458-25465
P356
10.1074/JBC.273.39.25458
P407
P577
1998-09-01T00:00:00Z