Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors.
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P1343
Identification of the TCL1 gene involved in T-cell malignanciesSite-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemiaThe tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix proteinThe mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemiaThe response to and repair of RAG-mediated DNA double-strand breaksSequence analysis of monoclonal antibodies derived from a patient with idiopathic thrombocytopenic purpura.neu protooncogene fused to an immunoglobulin heavy chain gene requires immunoglobulin light chain for cell surface expression and oncogenic transformation.Analysis of a T-cell tumor-specific breakpoint cluster at human chromosome 14q32.Juxtaposition of the T-cell receptor alpha-chain locus (14q11) and a region (14q32) of potential importance in leukemogenesis by a 14;14 translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasiaExpression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis.Cloning of the chromosome translocation breakpoint junction of the t(14;19) in chronic lymphocytic leukemia.Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.Expression of members of immunoglobulin gene family in somatic cell hybrids between human B and T cells.Molecular biology in medicine.Evolutionarily conserved TCR binding sites, identification of T cells in primary lymphoid tissues, and surprising trans-rearrangements in nurse shark.T cell receptor delta gene rearrangements in acute lymphoblastic leukemiaReciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines.The human VH repertoire: a restricted set of VH genes may be the target of immune regulation.Human T cell gamma genes are frequently rearranged in B-lineage acute lymphoblastic leukemias but not in chronic B cell proliferationsLineage-specific expression of a T cell receptor variable gene promoter controlled by upstream sequences.Surface expression of functional T cell receptor chains formed by interlocus recombination on human T lymphocytes.Molecular involvement of the pvt-1 locus in a gamma/delta T-cell leukemia bearing a variant t(8;14)(q24;q11) translocation.Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignanciesT-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11).Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response.Human heavy chain variable region gene diversity, organization, and expression.T-cell acute lymphoblastic leukemia and the associated basic helix-loop-helix gene SCL/tal.Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families.Fine mapping of chromosome 22 breakpoints within the breakpoint cluster region (bcr) implies a role for bcr exon 3 in determining disease duration in chronic myeloid leukemia.Molecular cytogenetic analysis of the breakpoint region at 6q21-22 in T-cell lymphoma/leukemia cell lines.Alternating purine-pyrimidine tracts may promote chromosomal translocations seen in a variety of human lymphoid tumours.The smaller human VH gene families display remarkably little polymorphism.Detection of chromosomal translocations in leukemia-lymphoma cells by polymerase chain reaction.Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments.Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32.Chromosomes, genes, and cancer.Human monoclonal antibodies against blood group antigens preferentially express a VH4-21 variable region gene-associated epitope.The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus.
P2860
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P2860
Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh-hant
name
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@en
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@nl
type
label
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@en
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@nl
prefLabel
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@en
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@nl
P2093
P1433
P1476
Fusion of an immunoglobulin va ...... associated with T cell tumors.
@en
P2093
P304
P356
10.1016/0092-8674(85)90243-0
P407
P433
P4510
P577
1985-12-01T00:00:00Z