A conformation- and phosphorylation-dependent antibody recognizing the paired helical filaments of Alzheimer's disease.
about
Tau and tauopathiesPropofol directly increases tau phosphorylationDexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcriptionMonoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.Co-occurrence of Alzheimer's disease ß-amyloid and τ pathologies at synapses.Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 miceSpecificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions.Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with agingIdentification of oligomers at early stages of tau aggregation in Alzheimer's disease.ASIP Outstanding Investigator Award Lecture. New approaches to the pathology and genetics of neurodegenerationMechanisms of tau-induced neurodegeneration.Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding.Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction.Genetic modifiers of tauopathy in Drosophila.AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies.Is there a neuropathology difference between mild cognitive impairment and dementia?Tau in Alzheimer disease and related tauopathies.Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorialDifferential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer's disease or corticobasal degeneration brainsThe relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's diseaseTau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnosticsDeveloping pharmacological therapies for Alzheimer disease.Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention.NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's diseaseAcetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies.Co-localization of glycogen synthase kinase-3 with neurofibrillary tangles and granulovacuolar degeneration in transgenic mice.Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors.Tau phosphorylation sites work in concert to promote neurotoxicity in vivo.Design of useful peptide antigens.Pin1 has opposite effects on wild-type and P301L tau stability and tauopathyProline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.Cyr61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons.Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease.The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features.Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain.Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo.Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia.Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.
P2860
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P2860
A conformation- and phosphorylation-dependent antibody recognizing the paired helical filaments of Alzheimer's disease.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
A conformation- and phosphoryl ...... aments of Alzheimer's disease.
@en
A conformation- and phosphoryl ...... aments of Alzheimer's disease.
@nl
type
label
A conformation- and phosphoryl ...... aments of Alzheimer's disease.
@en
A conformation- and phosphoryl ...... aments of Alzheimer's disease.
@nl
prefLabel
A conformation- and phosphoryl ...... aments of Alzheimer's disease.
@en
A conformation- and phosphoryl ...... aments of Alzheimer's disease.
@nl
P2093
P921
P1476
A conformation- and phosphoryl ...... laments of Alzheimer's disease
@en
P2093
P304
P356
10.1046/J.1471-4159.1997.69052087.X
P407
P577
1997-11-01T00:00:00Z