Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells.
about
Seven non-contiguous intracellular residues of the lutropin/choriogonadotropin receptor dictate the rate of agonist-induced internalization and its sensitivity to non-visual arrestinsβ-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila developmentThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsKappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytesAnalyzing the roles of multi-functional proteins in cells: The case of arrestins and GRKsStructure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor TraffickingCrystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual SubtypesStructure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptideAcidic amino acids flanking phosphorylation sites in the M2 muscarinic receptor regulate receptor phosphorylation, internalization, and interaction with arrestinsDifferential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor traffickingIdentification of a short linear sequence present in the C-terminal tail of the rat follitropin receptor that modulates arrestin-3 binding in a phosphorylation-independent fashionHow genetic errors in GPCRs affect their function: Possible therapeutic strategiesThreonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes.Identification of receptor binding-induced conformational changes in non-visual arrestins.The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activationFormation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor.Phosphorylation of C3a receptor at multiple sites mediates desensitization, β-arrestin-2 recruitment and inhibition of NF-κB activity in mast cellsOpioid receptor desensitization: mechanisms and its link to toleranceG-protein-coupled receptor phosphorylation: where, when and by whom.Recent advances on the δ opioid receptor: from trafficking to function.Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins.A single mutation in arrestin-2 prevents ERK1/2 activation by reducing c-Raf1 binding.Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling.The functional cycle of visual arrestins in photoreceptor cells.G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).Cargo- and compartment-selective endocytic scaffold proteins.Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors.Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.Disruption of parathyroid hormone and parathyroid hormone-related peptide receptor phosphorylation prolongs ERK1/2 MAPK activation and enhances c-fos expressionMu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neuronsManipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestinsInferring the lifetime of endosomal protein complexes by fluorescence recovery after photobleaching.Conformation of receptor-bound visual arrestin.Ligand directed signaling differences between rodent and human κ-opioid receptors.The role of phosphorylation in D1 dopamine receptor desensitization: evidence for a novel mechanism of arrestin associationEngineering visual arrestin-1 with special functional characteristicsSerotonin receptor signaling and regulation via β-arrestins.Morphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestinsGPCR monomers and oligomers: it takes all kinds.Regulation of arrestin binding by rhodopsin phosphorylation level.
P2860
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P2860
Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Targeted construction of phosp ...... onstitutive activity in cells.
@en
Targeted construction of phosp ...... onstitutive activity in cells.
@nl
type
label
Targeted construction of phosp ...... onstitutive activity in cells.
@en
Targeted construction of phosp ...... onstitutive activity in cells.
@nl
prefLabel
Targeted construction of phosp ...... onstitutive activity in cells.
@en
Targeted construction of phosp ...... onstitutive activity in cells.
@nl
P2093
P2860
P356
P1476
Targeted construction of phosp ...... onstitutive activity in cells.
@en
P2093
R I Abdryashitov
P2860
P304
P356
10.1074/JBC.274.11.6831
P407
P577
1999-03-01T00:00:00Z