Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesUnderstanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentThe Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsThe small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I.Neurodevelopmental effects of insulin-like growth factor signaling.Temporal and regional changes in IGF-1/IGF-1R signaling in the mouse brain after traumatic brain injury.Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells.Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancerNotch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160.Insulin-like growth factor-I-stimulated Akt phosphorylation and oligodendrocyte progenitor cell survival require cholesterol-enriched membranes.Directing traffic in neural cells: determinants of receptor tyrosine kinase localization and cellular responses.IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis.Endosomal recycling regulates Anthrax Toxin Receptor 1/Tumor Endothelial Marker 8-dependent cell spreading.Ceramide modulates HERG potassium channel gating by translocation into lipid raftsIGF-1 induces expression of zinc-finger protein 143 in colon cancer cells through phosphatidylinositide 3-kinase and reactive oxygen species.Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationInsulin-like growth factor-I E-peptide activity is dependent on the IGF-I receptor.Analysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy.Expression of IGF1R in normal breast tissue and subsequent risk of breast cancerAssociation of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women.Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1RExpression of the IGF axis is decreased in local prostate cancer but enhanced after benign prostate epithelial differentiation and TGF-β treatment.Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses.Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I protein.miR-1827 inhibits osteogenic differentiation by targeting IGF1 in MSMSCsMolecular biology of breast tumor progression: a view from the other side.Insulin growth factor binding proteins as therapeutic targets in type 2 diabetes.IGFBP-3 methylation-derived deficiency mediates the resistance to cisplatin through the activation of the IGFIR/Akt pathway in non-small cell lung cancer.Cellular distribution of the IGF-1R in corneal epithelial cells.beta-catenin mediates insulin-like growth factor-I actions to promote cyclin D1 mRNA expression, cell proliferation and survival in oligodendroglial culturesInsulin-like growth factor 1 (IGF-1) regulates prolactin, growth hormone, and IGF-1 receptor expression in the pituitary gland of the gilthead sea bream Sparus aurata.The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.CaMKIIα expression in a mouse model of NMDAR hypofunction schizophrenia: Putative roles for IGF-1R and TLR4.IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.
P2860
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P2860
Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@en
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@nl
type
label
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@en
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@nl
prefLabel
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@en
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@nl
P2093
P2860
P356
P1476
Insulin-like growth factor typ ...... tained phosphorylation of Akt.
@en
P2093
Alan Hochberg
Andrew P LeBeau
Clifton G Fulmer
Deborah A Lazzarino
Robert J Romanelli
Teresa L Wood
P2860
P304
22513-22524
P356
10.1074/JBC.M704309200
P407
P577
2007-06-01T00:00:00Z