Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. - Wikidata - wikimedia - TriplyDB

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

http://www.wikidata.org/entity/Q51629652

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CtIP is required to initiate replication-dependent interstrand crosslink repair MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms Update of the human and mouse Fanconi anemia genes Functions and regulation of the multitasking FANCM family of DNA motor proteins Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition Fancf-deficient mice are prone to develop ovarian tumours Expanded roles of the Fanconi anemia pathway in preserving genomic stability ATR activation and replication fork restart are defective in FANCM-deficient cells.FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling.Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability.Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling Regulation of homologous recombination in eukaryotes.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.Homologous recombination-dependent rescue of deficiency in the structural maintenance of chromosomes (Smc) 5/6 complex.Branching out with DNA helicases.Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress.Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma.Primary Ovarian Insufficiency Induced by Fanconi Anemia E Mutation in a Mouse Model.QTLs for murine red blood cell parameters in LG/J and SM/J F(2) and advanced intercross lines.FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1.A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair.The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks.Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks Helq acts in parallel to Fancc to suppress replication-associated genome instability.Concise Review: Getting to the Core of Inherited Bone Marrow Failures.

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Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

http://www.wikidata.org/entity/Q51629652

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

@en

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

@nl

type

label

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

@en

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

@nl

prefLabel

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

@en

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

@nl

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Human Molecular Genetics

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Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

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Anja van der Wal

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Anneke B Oostra

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Elly Delzenne-Goette

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Hans Joenje

http://www.w3.org/2001/XMLSchema#string

Hein te Riele

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Henri J van de Vrugt

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Johan P de Winter

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Jurgen Steltenpool

http://www.w3.org/2001/XMLSchema#string

Martin A Rooimans

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Martin van der Valk

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P2860

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.

Cloning and characterization of murine fanconi anemia group A gene: Fanca protein is expressed in lymphoid tissues, testis, and ovary

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

The emerging genetic and molecular basis of Fanconi anaemia

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3484-3495

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scholarly article

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10.1093/HMG/DDP297

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18

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18

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2009-06-26T00:00:00Z

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26325299

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19561169

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