Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.
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Identification of an endogenous ligand bound to a native orphan nuclear receptorThe transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytesAbnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient miceIntegrative analysis of metabolomics and transcriptomics data: a unified model framework to identify underlying system pathwaysDiagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data.Mapping of HNF4alpha target genes in intestinal epithelial cellsMicrobiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alphaMapping of liver-enriched transcription factors in the human intestine.Cooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line.Inactivation of hepatocyte nuclear factor-4{alpha} mediates alcohol-induced downregulation of intestinal tight junction proteins.pcaGoPromoter--an R package for biological and regulatory interpretation of principal components in genome-wide gene expression dataDifferentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4alpha knockdown in intestinal epithelial cells.Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.miR-30-HNF4γ and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomachLoss of CDX2 expression is associated with poor prognosis in colorectal cancer patients.Thyroid-Stimulating Hormone Increases HNF-4α Phosphorylation via cAMP/PKA Pathway in the LiverPreinvasive colorectal lesion transcriptomes correlate with endoscopic morphology (polypoid vs. nonpolypoid).Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.MicroRNA-feedback loop as a key modulator of liver tumorigenesis and inflammation.Post-transcriptional regulation of meprin α by the RNA-binding proteins Hu antigen R (HuR) and tristetraprolin (TTP)Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel diseaseUsing genomics to understand intestinal biology.In silico promoters: modelling of cis-regulatory context facilitates target predictio.Energy metabolism in intestinal epithelial cells during maturation along the crypt-villus axisEffects of weaning on intestinal crypt epithelial cells in piglets.Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.DNA methylation is required for the control of stem cell differentiation in the small intestine.Orphan nuclear receptors as targets for drug development.Control of nuclear receptor activities in metabolism by post-translational modifications.Current and emerging approaches to define intestinal epithelium-specific transcriptional networks.Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networksDeconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk.Meta-analysis of gene expression in human pancreatic islets after in vitro expansion.Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system.Hepatocyte nuclear factor-4 mediates apolipoprotein A-IV transcriptional regulation by fatty acid in newborn swine enterocytes.Genome-wide expression profiling during protection from colitis by regulatory T cells.
P2860
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P2860
Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@en
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@nl
type
label
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@en
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@nl
prefLabel
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@en
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@nl
P2093
P2860
P50
P1476
Metabolome, transcriptome, and ...... ng enterocyte differentiation.
@en
P2093
Anders Stegmann
Bjørn Quistorff
Janus B Larsen
Leif R Lund
Morten Hansen
Patricia Simon-Assmann
Yulan Wang
P2860
P304
P356
10.1152/PHYSIOLGENOMICS.00314.2005
P577
2006-07-25T00:00:00Z