Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage.
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Early articular cartilage degeneration in a developmental dislocation of the hip model results from activation of β-catenin.Significance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective.Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylationSynoviocytes protect cartilage from the effects of injury in vitroEpigenetic regulation during fetal femur development: DNA methylation matters.The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis.Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes.Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritisEpigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis.Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis.Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.Epigenetic modifications of interleukin-6 in synovial fibroblasts from osteoarthritis patientsNF-kappaB signaling: multiple angles to target OA.MicroRNA in osteoarthritis.Impact of inflammation on the osteoarthritic niche: implications for regenerative medicine.Epigenetic regulation of mmp-9 gene expression.Epigenetics in osteoarthritis and its implication for future therapeutics.Changes in the epigenetic status of the SOX-9 promoter in human osteoarthritic cartilage.ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes.Dual function of β-catenin in articular cartilage growth and degeneration at different stages of postnatal cartilage development.DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytesEarly cartilage degeneration in a rat experimental model of developmental dysplasia of the hip.Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis.A whole-genome transcriptome analysis of articular chondrocytes in secondary osteoarthritis of the hip.Cellular and molecular changes to chondrocytes in an in vitro model of developmental dysplasia of the hip‑an experimental model of DDH with swaddling position
P2860
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P2860
Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Cellular and epigenetic featur ...... aged control and OA cartilage.
@en
Cellular and epigenetic featur ...... aged control and OA cartilage.
@nl
type
label
Cellular and epigenetic featur ...... aged control and OA cartilage.
@en
Cellular and epigenetic featur ...... aged control and OA cartilage.
@nl
prefLabel
Cellular and epigenetic featur ...... aged control and OA cartilage.
@en
Cellular and epigenetic featur ...... aged control and OA cartilage.
@nl
P2093
P356
P1476
Cellular and epigenetic featur ...... aged control and OA cartilage.
@en
P2093
Helmtrud I Roach
Marco A da Silva
Nicholas M P Clarke
Norikazu Yamada
P304
P356
10.1002/JOR.20799
P577
2009-05-01T00:00:00Z