Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.
about
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymesTwo distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.Regulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsThe role of deubiquitinating enzymes in synaptic function and nervous system diseasesLa FAM fatale: USP9X in development and diseaseStructural Requirements for PACSIN/Syndapin Operation during Zebrafish Embryonic Notochord DevelopmentDissection of USP catalytic domains reveals five common insertion pointsNotch ligand endocytosis: mechanistic basis of signaling activityThe ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9XThe epsin protein family: coordinators of endocytosis and signalingNeuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actinEmbryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in miceLoss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesisThe atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in DrosophilaThe clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis.Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development.Endocytic internalization routes required for delta/notch signalingEnrichment of O-GlcNAc modified proteins by the periodate oxidation-hydrazide resin capture approachThe association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin.Neuralized promotes basal to apical transcytosis of delta in epithelial cellsKuz and TACE can activate Notch independent of ligandRole of glycans and glycosyltransferases in the regulation of Notch signalingOptical tweezers studies on Notch: single-molecule interaction strength is independent of ligand endocytosis.Effete, an E2 ubiquitin-conjugating enzyme with multiple roles in Drosophila development and chromatin organizationDrosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signalingEpsin is required for Dishevelled stability and Wnt signalling activation in colon cancer developmentThe endocytic adaptor Eps15 controls marginal zone B cell numbersThe functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling.Endocytic adaptors--social networking at the plasma membrane.Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activationEmerging molecular targets for the treatment of pre-eclampsia.Proteasome, but not autophagy, disruption results in severe eye and wing dysmorphia: a subunit- and regulator-dependent process in Drosophila.Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis.New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.Notch ligand ubiquitylation: what is it good for?Structure-function analysis of delta trafficking, receptor binding and signaling in DrosophilaBalancing act: deubiquitinating enzymes in the nervous system.Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals.Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized.
P2860
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P2860
Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Fat facets and Liquid facets p ...... naling in the signaling cells.
@en
Fat facets and Liquid facets p ...... naling in the signaling cells.
@nl
type
label
Fat facets and Liquid facets p ...... naling in the signaling cells.
@en
Fat facets and Liquid facets p ...... naling in the signaling cells.
@nl
prefLabel
Fat facets and Liquid facets p ...... naling in the signaling cells.
@en
Fat facets and Liquid facets p ...... naling in the signaling cells.
@nl
P2093
P356
P1433
P1476
Fat facets and Liquid facets p ...... naling in the signaling cells.
@en
P2093
Erin Fitch
Erin Overstreet
Janice A Fischer
P304
P356
10.1242/DEV.01434
P407
P577
2004-10-06T00:00:00Z