Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.
about
Inflammation and Alzheimer's diseasePrion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegenerationLymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo.LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis.The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individualsAnalysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies.Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics.Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects.Differences in risk factors for dementia with neurodegenerative traits and for vascular dementia.Influence of Alpha-2-Macroglobulin 5 bp I/D and Ile1000Val polymorphisms on the susceptibility of Alzheimer's disease: a systematic review and meta-analysis of 52 studies.A chemically modified preparation of alpha2-macroglobulin binds beta-amyloid peptide with increased affinity and inhibits Abeta cytotoxicity.Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study.Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons.Genetic association of argyrophilic grain disease with polymorphisms in alpha-2 macroglobulin and low-density lipoprotein receptor-related protein genes.Elevation of LDL receptor-related protein levels via ligand interactions in Alzheimer disease and in vitro.Lack of association of the two polymorphisms in alpha-2 macroglobulin with Alzheimer disease.Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population.Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.An association between a subset of Finnish late-onset Alzheimer's disease and alpha2-macroglobulin.
P2860
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P2860
Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Genetic association of an alph ...... phism and Alzheimer's disease.
@en
Genetic association of an alpha2-macroglobulin
@nl
type
label
Genetic association of an alph ...... phism and Alzheimer's disease.
@en
Genetic association of an alpha2-macroglobulin
@nl
prefLabel
Genetic association of an alph ...... phism and Alzheimer's disease.
@en
Genetic association of an alpha2-macroglobulin
@nl
P2093
P2860
P356
P1476
Genetic association of an alph ...... rphism and Alzheimer's disease
@en
P2093
A Clatworthy
G W Rebeck
H Staehelin
J H Growdon
K Zuchowski
P2860
P304
P356
10.1093/HMG/7.12.1953
P577
1998-11-01T00:00:00Z