bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs.
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Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxesbcl-2 gene enables rescue from in vitro myelosuppression (bone marrow cell death) induced by chemotherapyIs drug-induced toxicity a good predictor of response to neo-adjuvant chemotherapy in patients with breast cancer?--a prospective clinical studyTargeting the Bcl-2 family for cancer therapyApoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95-CD95 ligand interaction5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteinsSynergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell linesCcdc94 protects cells from ionizing radiation by inhibiting the expression of p53Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytesSubstantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease.Role of the Bcl-2 gene family in prostate cancer progression and its implications for therapeutic intervention.EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer.Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance.Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiationMitochondria: a target for cancer therapy.Expression of a specific marker of avian programmed cell death in both apoptosis and necrosis.Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.Bcl-2 protein expression in lung cancer and close correlation with neuroendocrine differentiationThe mitochondrial death pathway: a promising therapeutic target in diseasesThe cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entryBcl-2 expression and response to chemotherapy in colorectal adenocarcinomas.Expression of apoptosis-regulatory genes in lung tumour cell lines: relationship to p53 expression and relevance to acquired drug resistanceBcl-2 and the regulation of programmed cell death.The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosisRecessive mutations in a common pathway block thymocyte apoptosis induced by multiple signals.R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.Mitochondrial medicine: pharmacological targeting of mitochondria in diseaseInterleukin 7-dependent B lymphocyte precursor cells are ultrasensitive to apoptosis.Bcl-2-family proteins and hematologic malignancies: history and future prospects.The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.Gene expression profiling analysis of ovarian cancerLentiviral short hairpin RNA screen of genes associated with multidrug resistance identifies PRP-4 as a new regulator of chemoresistance in human ovarian cancer.Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103.Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis.Increased manganese superoxide dismutase expression or treatment with manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cellsBcl-2 expression significantly correlates with thymidylate synthase expression in colorectal cancer patients.Correlating notch signaling with thymocyte maturation.Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.Evolution of BCL-2/IgH hybrid gene RNA expression during treatment of T(14;18)-bearing follicular lymphomas.
P2860
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P2860
bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@en
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@nl
type
label
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@en
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@nl
prefLabel
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@en
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@nl
P1433
P1476
bcl-2 gene transfer increases ...... ltiple chemotherapeutic drugs.
@en
P2093
P304
P407
P577
1992-10-01T00:00:00Z