Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase.
about
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sitesCrystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognitionCrystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNAStructural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residuesBiphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylaseThe DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcriptionThe main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosineRole of base excision repair in maintaining the genetic and epigenetic integrity of CpG sitesA 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatchDependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairsExcision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.Recent advances in the structural mechanisms of DNA glycosylasesFormation and repair of tobacco carcinogen-derived bulky DNA adductsDEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.Efficient repair of all types of single-base mismatches in recombination intermediates in Chinese hamster ovary cells. Competition between long-patch and G-T glycosylase-mediated repair of G-T mismatches.Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNAThe human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.7,8-Dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases.Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors.Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylaseSequence context-specific mutagenesis and base excision repair.Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase.Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA.Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.Direct real time observation of base flipping by the EcoRI DNA methyltransferase.Initiation of strand incision at G:T and O(6)-methylguanine:T base mismatches in DNA by human cell extracts.Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands.Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts.Base flip in DNA studied by molecular dynamics simulationsof differently-oxidized forms of methyl-CytosineSpecificity of human thymine DNA glycosylase depends on N-glycosidic bond stability.Correlation between sequence-dependent glycosylase repair and the thermal stability of oligonucleotide duplexes containing 1, N6-ethenoadenine.Kinetics of the action of thymine DNA glycosylase.Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer.The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.Impact of DNA physical properties on local sequence bias of human mutation
P2860
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P2860
Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Base analog and neighboring ba ...... cific thymine DNA-glycosylase.
@en
Base analog and neighboring ba ...... cific thymine DNA-glycosylase.
@nl
type
label
Base analog and neighboring ba ...... cific thymine DNA-glycosylase.
@en
Base analog and neighboring ba ...... cific thymine DNA-glycosylase.
@nl
prefLabel
Base analog and neighboring ba ...... cific thymine DNA-glycosylase.
@en
Base analog and neighboring ba ...... cific thymine DNA-glycosylase.
@nl
P2093
P356
P1433
P1476
Base analog and neighboring ba ...... ecific thymine DNA-glycosylase
@en
P2093
Day RS 3rd
Gallinari P
Goodman MF
Sibghat-Ullah
P304
12926-12932
P356
10.1021/BI961022U
P407
P50
P577
1996-10-01T00:00:00Z