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Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion holeFundamental challenges in mechanistic enzymology: progress toward understanding the rate enhancements of enzymesComplete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificityHint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferasesCrystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovoseCrystal structure of delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilizationInhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domainDetection of large pKa perturbations of an inhibitor and a catalytic group at an enzyme active site, a mechanistic basis for catalytic power of many enzymes'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexesToward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphataseStructural determinants for ligand binding and catalysis of triosephosphate isomeraseCrystal structure of triosephosphate isomerase complexed with 2-phosphoglycolate at 0.83-A resolutionAtomic resolution analysis of the catalytic site of an aspartic proteinase and an unexpected mode of binding by short peptidesTrypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysisElucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D. 1. Mutagenesis and Structural Studies † , ‡Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pHThe Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-ray DiffractionShort strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase.Statistical Coupling Analysis of Aspartic Proteinases Based on Crystal Structures of the Trichoderma reesei Enzyme and Its Complex with Pepstatin ACrystallographic structure of xanthorhodopsin, the light-driven proton pump with a dual chromophoreDissecting the paradoxical effects of hydrogen bond mutations in the ketosteroid isomerase oxyanion holeStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Importance of Residues in the Orotate Binding SiteBinding Energy and Catalysis by d -Xylose Isomerase: Kinetic, Product, and X-ray Crystallographic Analysis of Enzyme-Catalyzed Isomerization of ( R )-GlyceraldehydeEvaluating the Catalytic Contribution from the Oxyanion Hole in Ketosteroid IsomeraseAtomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD + and Fluoroalcohols Define Strained Michaelis ComplexesQuantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active siteStructural insights into the proton pumping by unusual proteorhodopsin from nonmarine bacteriaUnexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiaminStructural and thermodynamic consequences of burial of an artificial ion pair in the hydrophobic interior of a proteinStructural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like proteaseAtomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion holeThe 1.1 Å resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data BankSome Brief Notes on Theoretical and Experimental Investigations of Intramolecular Hydrogen BondingAn alternate proton acceptor for excited-state proton transfer in green fluorescent protein: rewiring GFPProton bridging in the interactions of thrombin with hirudin and its mimics.Effects of high pressure on solvent isotope effects of yeast alcohol dehydrogenaseHigh-precision measurement of hydrogen bond lengths in proteins by nuclear magnetic resonance methods.Using unnatural amino acids to probe the energetics of oxyanion hole hydrogen bonds in the ketosteroid isomerase active site.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
The low barrier hydrogen bond in enzymatic catalysis.
@en
The low barrier hydrogen bond in enzymatic catalysis.
@nl
type
label
The low barrier hydrogen bond in enzymatic catalysis.
@en
The low barrier hydrogen bond in enzymatic catalysis.
@nl
prefLabel
The low barrier hydrogen bond in enzymatic catalysis.
@en
The low barrier hydrogen bond in enzymatic catalysis.
@nl
P2093
P2860
P356
P1476
The low barrier hydrogen bond in enzymatic catalysis.
@en
P2093
P2860
P304
25529-25532
P356
10.1074/JBC.273.40.25529
P407
P577
1998-10-01T00:00:00Z