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Glycolaldehyde induces apoptosis in a human breast cancer cell lineTargeting mitochondria by Zn(II)N-alkylpyridylporphyrins: the impact of compound sub-mitochondrial partition on cell respiration and overall photodynamic efficacyInduction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin.Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsAnticancer therapeutic potential of Mn porphyrin/ascorbate systemBioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn siteA combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itselfImpact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.Escherichia coli exhibits negative chemotaxis in gradients of hydrogen peroxide, hypochlorite, and N-chlorotaurine: products of the respiratory burst of phagocytic cellsSimple biological systems for assessing the activity of superoxide dismutase mimics.Protein damage by photo-activated Zn(II) N-alkylpyridylporphyrins.The potential of Zn(II) N-alkylpyridylporphyrins for anticancer therapy.Photodynamic therapy: current status and future directions.Is there a role for neurotrophic factors and their receptors in augmenting the neuroprotective effect of (-)-epigallocatechin-3-gallate treatment of sciatic nerve crush injury?Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity.An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation.Photosensitizing action of isomeric zinc N-methylpyridylporphyrins in human carcinoma cells.Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics.Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications.High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coliEffect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(II) N-alkylpyridylporphyrins.Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat.Manganese supplementation relieves the phenotypic deficits seen in superoxide-dismutase-null Escherichia coli.Is reduction of the sulfonated tetrazolium 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-2-tetrazolium 5-carboxanilide a reliable measure of intracellular superoxide production?Superoxide-dependence of the short chain sugars-induced mutagenesis.Triosephosphates are toxic to superoxide dismutase-deficient Escherichia coli.Cationic amphiphilic Zn-porphyrin with high antifungal photodynamic potency.HgCl2 increases the methemoglobin prooxidant activity. Possible mechanism of Hg2+-induced lipid peroxidation in erythrocytes.The Contribution of Superoxide Radical to Cadmium Toxicity in E. coli.Important cellular targets for antimicrobial photodynamic therapy.Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution.Inactivation of metabolic enzymes by photo-treatment with zinc meta N-methylpyridylporphyrin.Post-illumination cellular effects of photodynamic treatment.Possible role of antioxidative capacity of (-)-epigallocatechin-3-gallate treatment in morphological and neurobehavioral recovery after sciatic nerve crush injury.Hemoglobin-catalyzed lipid peroxidation in the presence of mercuric chloride.
P50
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Ludmil T. Benov
@ast
Ludmil T. Benov
@en
Ludmil T. Benov
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Ludmil T. Benov
@nl
Ludmil T. Benov
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type
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Ludmil T. Benov
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Ludmil T. Benov
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Ludmil T. Benov
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Ludmil T. Benov
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Ludmil T. Benov
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prefLabel
Ludmil T. Benov
@ast
Ludmil T. Benov
@en
Ludmil T. Benov
@es
Ludmil T. Benov
@nl
Ludmil T. Benov
@sl
P106
P1153
16164974800
P31
P496
0000-0002-0205-0146