Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes
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The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanomaHuman papillomavirus induced transformation in cervical and head and neck cancersHuman papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiationThe role of the E6-p53 interaction in the molecular pathogenesis of HPV.Human papillomavirus infections: epidemiology, pathogenesis, and therapy.The DNA damage response in viral-induced cellular transformationThe E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradationBiological activities and molecular targets of the human papillomavirus E7 oncoprotein.HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress.Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture.Human papillomavirus (HPV) E7 induces prolonged G2 following S phase reentry in differentiated human keratinocytes.Papillomaviruses: Viral evolution, cancer and evolutionary medicineHuman papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes.Effects of human papillomavirus (HPV) type 16 oncoproteins on the expression of involucrin in human keratinocytesHuman papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implicationsPost-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle.Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification.Laboratory and clinical aspects of human papillomavirus testingEmerging role of mutations in epigenetic regulators including MLL2 derived from The Cancer Genome Atlas for cervical cancer.Role of proteomics in translational research in cervical cancer.Separation of C/EBPalpha-mediated proliferation arrest and differentiation pathways.Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer.Induction of tetrasomy by human papillomavirus type 16 E7 protein is independent of pRb binding and disruption of differentiation.Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein.Position paper--HPV and the primary prevention of cancer; improving vaccine uptake by paediatricians.In vitro three-dimensional (3D) models in cancer research: an update.At a crossroads: human DNA tumor viruses and the host DNA damage response.Model systems to study the life cycle of human papillomaviruses and HPV-associated cancers.Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral Replication.Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells.Rb-independent induction of apoptosis by bovine papillomavirus type 1 E7 in response to tumor necrosis factor alpha.The SV40 large T oncoprotein disrupts DNA-binding of the cell cycle-regulated transcriptional repressor CDF.Mechanisms by which HPV Induces a Replication Competent Environment in Differentiating Keratinocytes.Transcriptional regulation of genes involved in keratinocyte differentiation by human papillomavirus 16 oncoproteins.Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice.Differential expression of p53 and p21 in low grade cervical squamous intraepithelial lesions infected with low, intermediate, and high risk human papillomaviruses.The cytokines tumor necrosis factor-alpha (TNF-alpha ) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the human papillomavirus-16 E7 oncoprotein.Characterization of Skn-1a/i POU domain factors and linkage to papillomavirus gene expression.Human papilloma virus: An etiological and prognostic factor for oral cancer?Alterations in cyclin-dependent kinase 2 function during differentiation of primary human keratinocytes.
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Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes
description
article
@en
im Oktober 1995 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в жовтні 1995
@uk
name
Differentiation-dependent up-r ...... l differentiated keratinocytes
@en
Differentiation-dependent up-r ...... l differentiated keratinocytes
@nl
type
label
Differentiation-dependent up-r ...... l differentiated keratinocytes
@en
Differentiation-dependent up-r ...... l differentiated keratinocytes
@nl
prefLabel
Differentiation-dependent up-r ...... l differentiated keratinocytes
@en
Differentiation-dependent up-r ...... l differentiated keratinocytes
@nl
P2093
P356
P1433
P1476
Differentiation-dependent up-r ...... l differentiated keratinocytes
@en
P2093
D C Schmidt-Grimminger
T R Broker
P304
P356
10.1101/GAD.9.19.2335
P577
1995-10-01T00:00:00Z