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Increased response to morphine in mice lacking protein kinase C epsilonNeuropeptide-Y in the paraventricular nucleus increases ethanol self-administrationComparison of ethanol locomotor sensitization in adolescent and adult DBA/2J mice.Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbensPreclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptomsComparison of the adolescent and adult mouse prefrontal cortex proteomeMetabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intakeThe mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice.GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilonPharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release.Coregulation of ethanol discrimination by the nucleus accumbens and amygdala.GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice.The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions.Norepinephrine and serotonin receptors in the paraventricular nucleus interactively modulate ethanol consumptionDecreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.Alcohol alters the activation of ERK1/2, a functional regulator of binge alcohol drinking in adult C57BL/6J mice.Adolescent C57BL/6J mice show elevated alcohol intake, but reduced taste aversion, as compared to adult mice: a potential behavioral mechanism for binge drinking.mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in ratsActivation of group II metabotropic glutamate receptors inhibits the discriminative stimulus effects of alcohol via selective activity within the amygdala.Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol.Intra-amygdala inhibition of ERK(1/2) potentiates the discriminative stimulus effects of alcohol.Increased sensitivity to alcohol induced changes in ERK Map kinase phosphorylation and memory disruption in adolescent as compared to adult C57BL/6J mice.Operant ethanol self-administration increases extracellular-signal regulated protein kinase (ERK) phosphorylation in reward-related brain regions: selective regulation of positive reinforcement in the prefrontal cortex of C57BL/6J mice.CaMKIIα-GluA1 Activity Underlies Vulnerability to Adolescent Binge Alcohol Drinking.The effects of repeated corticosterone exposure on the interoceptive effects of alcohol in ratsEnhanced AMPA receptor activity increases operant alcohol self-administration and cue-induced reinstatementEffects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats.Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats.Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082.Ethanol-induced alterations of c-Fos immunoreactivity in specific limbic brain regions following ethanol discrimination training.Cannabinoid CB1 receptor inhibition blunts adolescent-typical increased binge alcohol and sucrose consumption in male C57BL/6J miceCue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEPOverexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.Specific and nonspecific effects of naltrexone on goal-directed and habitual models of alcohol seeking and drinking.Microdialysis in the mouse nucleus accumbens: a method for detection of monoamine and amino acid neurotransmitters with simultaneous assessment of locomotor activity.Deletion of the 5-HT(3A)-receptor subunit blunts the induction of cocaine sensitization.CaMKII inhibition in the prefrontal cortex specifically increases the positive reinforcing effects of sweetened alcohol in C57BL/6J mice.Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice.
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P50
description
researcher ORCID ID = 0000-0002-6860-7955
@en
wetenschapper
@nl
name
Clyde W Hodge
@ast
Clyde W Hodge
@en
Clyde W Hodge
@nl
type
label
Clyde W Hodge
@ast
Clyde W Hodge
@en
Clyde W Hodge
@nl
prefLabel
Clyde W Hodge
@ast
Clyde W Hodge
@en
Clyde W Hodge
@nl
P31
P496
0000-0002-6860-7955