Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
about
Mammalian lipoxygenases and their biological relevance12- and 15-lipoxygenases in adipose tissue inflammationSystematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesiaFunctional and pathological roles of the 12- and 15-lipoxygenasesDiscovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapyA high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2A potent and selective inhibitor targeting human and murine 12/15-LOX.Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapiesInhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes.Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.The potential of 12/15-lipoxygenase inhibitors in stroke therapy.Eicosanoids, β-cell function, and diabetesA high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors.Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with in Vitro and ex Vivo Anti-inflammatory Properties.Pseudoperoxidase investigations of hydroperoxides and inhibitors with human lipoxygenasesSynthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenaseQuantitative metabolic profiling of lipid mediators.15-Lipoxygenase inhibitors: a patent review.2-Arylbenzo[b]furan derivatives as potent human lipoxygenase inhibitors.Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor.Enzymatic Studies of Isoflavonoids as Selective and Potent Inhibitors of Human Leukocyte 5-Lipo-Oxygenase.
P2860
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P2860
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@ast
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@en
type
label
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@ast
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@en
prefLabel
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@ast
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@en
P2093
P2860
P50
P356
P1476
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
@en
P2093
David J Maloney
Eric Hoobler
Ganesha Rai
J Brian Jameson
Lena Schultz
Michelle Armstrong
Theodore R Holman
William Leister
P2860
P304
P356
10.1021/JM1008852
P407
P577
2010-10-01T00:00:00Z