Characterization of a novel protein (FGFRL1) from human cartilage related to FGF receptors.
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Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissuesFGF-10 and its receptor exhibit bidirectional paracrine targeting to urothelial and smooth muscle cells in the lower urinary tractMicroRNA-210: a unique and pleiotropic hypoxamirFibroblast growth factor signaling in skeletal development and diseaseInhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical applicationFibroblast growth factors as tissue repair and regeneration therapeutics.Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragmMultiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null miceExtending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFsCellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.FGFRL1 is a neglected putative actor of the FGF signalling pathway present in all major metazoan phylaComparison of the receptor FGFRL1 from sea urchins and humans illustrates evolution of a zinc binding motif in the intracellular domain.The FGFRL1 receptor is shed from cell membranes, binds fibroblast growth factors (FGFs), and antagonizes FGF signaling in Xenopus embryos-Glial and stem cell expression of murine Fibroblast Growth Factor Receptor 1 in the embryonic and perinatal nervous systemExamination of FGFRL1 as a candidate gene for diaphragmatic defects at chromosome 4p16.3 shows that Fgfrl1 null mice have reduced expression of Tpm3, sarcomere genes and Lrtm1 in the diaphragm.Targeted disruption of the intracellular domain of receptor FgfrL1 in mice.Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signalingThe Fibroblast Growth Factor signaling pathwayFGFs, their receptors, and human limb malformations: clinical and molecular correlations.Frequent loss of genome gap region in 4p16.3 subtelomere in early-onset type 2 diabetes mellitus.A net-like structure with pores is observed during cell fusion induced by the receptor FGFRL1.Genome-wide comparison of FGFRL1 with structurally related surface receptors.Fibroblast growth factor receptor like-1 (FGFRL1) interacts with SHP-1 phosphatase at insulin secretory granules and induces beta-cell ERK1/2 protein activation.Receptor FGFRL1 does not promote cell proliferation but induces cell adhesionMEMO1 drives cranial endochondral ossification and palatogenesis.Brain regeneration from pluripotent stem cells in planarian.Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.Extracellular interactome of the FGF receptor-ligand system: complexities and the relative simplicity of the worm.Receptor FGFRL1 acts as a tumor suppressor in nude mice when overexpressed in HEK 293 Tet-On cells.Biology of FGFRL1, the fifth fibroblast growth factor receptor.Constitutive gene expression and the specification of tissue identity in adult planarian biology.miR-210: the master hypoxamir.Role of FGFRL1 and other FGF signaling proteins in early kidney development.Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations.Emerging biomarkers in head and neck cancer in the era of genomics.Fibroblast growth factor family as a potential target in the treatment of hepatocellular carcinoma.An integrated genomic, transcriptional and protein investigation of FGFRL1 as a putative 4p16.3 deletion target in bladder cancer.Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium.Theoretical studies on FGFR isoform selectivity of FGFR1/FGFR4 inhibitors by molecular dynamics simulations and free energy calculations.FGFR-related gene nou-darake restricts brain tissues to the head region of planarians.
P2860
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P2860
Characterization of a novel protein (FGFRL1) from human cartilage related to FGF receptors.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Characterization of a novel pr ...... lage related to FGF receptors.
@ast
Characterization of a novel pr ...... lage related to FGF receptors.
@en
type
label
Characterization of a novel pr ...... lage related to FGF receptors.
@ast
Characterization of a novel pr ...... lage related to FGF receptors.
@en
prefLabel
Characterization of a novel pr ...... lage related to FGF receptors.
@ast
Characterization of a novel pr ...... lage related to FGF receptors.
@en
P356
P1433
P1476
Characterization of a novel pr ...... ilage related to FGF receptors
@en
P2093
Wiedemann M
P304
P356
10.1006/GENO.2000.6332
P50
P577
2000-10-01T00:00:00Z