Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteines.
about
Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and functionHuman RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processingDetermination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs.Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysis.Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver functionDefining the factors that contribute to on-target specificity of antisense oligonucleotides.Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria.Conformational analysis of oxidized peptide fragments of the C-terminal redox center in thioredoxin reductases by NMR spectroscopy.Synthesis, Redox Properties, and Conformational Analysis of Vicinal Disulfide Ring Mimics.Molecular Mechanisms of Antisense Oligonucleotides.
P2860
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P2860
Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteines.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@ast
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@en
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@nl
type
label
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@ast
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@en
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@nl
prefLabel
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@ast
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@en
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@nl
P2093
P2860
P356
P1476
Human RNase H1 activity is reg ...... ed between adjacent cysteines.
@en
P2093
Hongjiang Wu
Jared J Drader
Josh G Nichols
Sherilynn M Manalili
Stanley T Crooke
Steven A Hofstadler
Walt F Lima
P2860
P304
14906-14912
P356
10.1074/JBC.M211279200
P407
P577
2002-12-08T00:00:00Z