LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function. - sprookjes - yvandenbroek - TriplyDB

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.

http://www.wikidata.org/entity/Q35193215

about

Pancreatic Cancer Genetics Epidemiology and Inherited Predisposition for Sporadic Pancreatic Adenocarcinoma Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis Regulation of Cellular Identity in Cancer Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21 Large-scale quality analysis of published ChIP-seq data.An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos Nuclear receptors and pathogenesis of pancreatic cancer.Regeneration and repair of the exocrine pancreas.Identification of transcription factors and single nucleotide polymorphisms of Lrh1 and its homologous genes in Lrh1-knockout pancreas of mice.The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma NR5A nuclear receptor Hr39 controls three-cell secretory unit formation in Drosophila female reproductive glands Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.Pathogenesis of pancreatic cancer: lessons from animal models.Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes.Exocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cells Transcriptional control of mammalian pancreas organogenesis.Insulin-like genes in ascidians: findings in Ciona and hypotheses on the evolutionary origins of the pancreas Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development Identification of a functional enhancer variant within the chronic pancreatitis-associated SPINK1 c.101A>G (p.Asn34Ser)-containing haplotype.LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression.Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease.Nuclear receptor NR5A2 controls neural stem cell fate decisions during development.Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.Identification of the principal transcriptional regulators for low-fat and high-fat meal responsive genes in small intestine Putting GWAS to the functional test: NR5A2 and pancreatic cancer risk.ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis.FGF21 Is an Exocrine Pancreas Secretagogue.Association between NR5A2 and the risk of pancreatic cancer, especially among Caucasians: a meta-analysis of case-control studies.Arid1a restrains Kras-dependent changes in acinar cell identity.

P2860

Q26765235-F233A890-3E80-44B2-97C2-B6B99BA62C33 Q26801418-99F28E98-0D33-4762-8A7B-34B14BFA0AD3 Q27334054-25A9D551-A178-4DAC-AD0E-9CAA47B65204 Q28086849-B4AE163D-DDAC-44E5-8507-14777DD85EF3 Q28505235-327CA5CE-A5C0-410E-8ECA-41BC35527CF7 Q28511736-8F71C91A-F10B-46F9-835C-2E604AF3407B Q28591095-68AD83D8-2A9E-4D17-8267-194ABE3F738F Q28591563-E6CDA143-514F-4219-9B66-3C28BACCC950 Q29248193-CD946163-0252-4809-A15B-B02E50FF246F Q30717456-0298A8BE-A97B-4573-AC00-632B824CA8C1 Q33786699-2354CE24-2E83-4BCD-9451-75DA5F16A482 Q34168476-EE391502-170F-4866-91B7-F20022E8E4F6 Q35071666-ABD045A7-A4E2-4023-B15E-3BD9FA9BEC96 Q35148501-52980F75-55B5-4553-B3C6-0F1570A3A119 Q35954277-A6474159-AFC4-44A1-8213-97230ADECFE2 Q36095776-3F10E0ED-26F4-4FA2-B158-5D263303533A Q36317537-5BE1026F-8912-4252-BF0A-96C8826CA330 Q37589374-86338176-6CB6-4C9B-B08D-59176D6201A9 Q37610670-912F0AA8-724F-4BE3-9E7A-3004D07E04B0 Q37687791-E14131CD-FB82-41F1-8ACC-F9050ABD986D Q38022404-C10E1264-3CD7-4EE4-B702-553D5CBDFAB6 Q38162099-A7A4F42C-1E13-45D9-A97C-0FF7EDFEA419 Q38265951-CB6DE5DC-B044-45DA-82E9-E23B85578E1E Q38291493-856349AC-D4D4-43B5-AC9C-93F95B44035C Q38757404-1223890F-FD00-4B17-937D-C26C81B9405B Q38936732-D17FCCDA-6538-47A0-8A5D-625DD424FB39 Q39156056-E780418A-6F69-4CD3-B698-64F8ED6021FA Q39384816-3B6212CD-A966-4E7B-84C1-AD33C93C4AAC Q41737306-931768E2-BF78-4029-880A-786CAD44EE6B Q42032252-CAB5A8DB-2532-4082-86B1-880560ED73CD Q42269245-0D2E311C-0E8A-4F6B-898E-99F765C6E775 Q42643730-0ED7DC79-AAE2-4ABE-8A98-FAEAB39B9724 Q45415868-19714159-A17C-42F3-A645-721F22FBD638 Q46563062-2B53D44F-8DC6-4027-9780-06BAD3CE4C16 Q50001765-D2CBB29C-FCD7-4A5D-9DB1-B391E6423EB5 Q51061806-5152B68F-82F7-4F3A-B1C9-FAF541EE334C Q51189900-B2D14214-40BD-4E42-8EAB-21784B103F5D Q54975203-37A81E6D-D46F-4894-A5FF-27AFCE596755 Q55713410-A8291731-7571-439D-94DD-0E6E16D9CBFE

P2860

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.

http://www.wikidata.org/entity/Q35193215

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

LRH-1 and PTF1-L coregulate an ...... etwork for digestive function.

@ast

LRH-1 and PTF1-L coregulate an ...... etwork for digestive function.

@en

type

label

LRH-1 and PTF1-L coregulate an ...... etwork for digestive function.

@ast

LRH-1 and PTF1-L coregulate an ...... etwork for digestive function.

@en

prefLabel

LRH-1 and PTF1-L coregulate an ...... etwork for digestive function.

@ast

LRH-1 and PTF1-L coregulate an ...... etwork for digestive function.

@en

P1433

Q35193215-5F86B32B-77FA-4CBF-A693-02DFEB17C907

P1476

Q35193215-0103866D-5285-4CCA-9BD2-E8EE41F6EDCC

P2093

Q35193215-52FFD6AF-BEEB-42A3-AD9C-3F57E6B6FF08

Q35193215-A56E94EA-C95E-4296-B510-A30244A17867

Q35193215-B6278BDE-3288-4F26-8316-20F62561FCEB

Q35193215-C9FEF9A7-8B68-490E-9AD1-12766BF85158

Q35193215-EAEC1943-E9E4-4ED3-8F1C-4FF469AB0335

P2860

Q35193215-13E479F3-1CF4-4E4B-AD76-DB665ED06943

Q35193215-1611E0FC-29C0-429E-95E5-D98CE108B352

Q35193215-1B5FC39A-50D3-4605-9C64-46A331EC04D6

Q35193215-271F02E0-C4A3-4407-BD53-9E02AF8A37F5

Q35193215-2D111B1A-F1EF-4F7B-8AD8-D5985FD0E0E9

Q35193215-39C7A7D3-D83E-4A65-AFC0-00F96255DCA3

Q35193215-3FDC30B7-59E3-4DD1-BACF-CFDECC7DE461

Q35193215-5D3E5155-211D-4473-A1D8-6483809F8F78

Q35193215-75D47B83-AF67-4B6F-BA1E-24F420914B44

Q35193215-76C4D266-78C6-4B7D-97E5-5B8C0A0430C6

P304

Q35193215-EE856EFA-833B-4D45-93AE-FDC2E20DE85A

P31

Q35193215-D2B29185-EA1B-41C6-9035-03334D1FE4F8

P356

Q35193215-3E135154-840F-421B-9A1C-37AA6DB7FDF6

P433

Q35193215-DEED1361-F6A3-43F8-B697-D9B2923B6F5D

P478

Q35193215-DF9A21E1-7AA9-4A27-AD33-E0E6BEC21608

P50

Q35193215-1C431BC7-7265-433A-BD24-472FE791C4F4

Q35193215-B7664C78-0274-44A4-BD58-D2741BF6B409

P577

Q35193215-BFD61517-15B7-4E29-B37A-479BF7D981A4

P5875

Q35193215-30232EDC-E5B2-486A-9F99-D5A65DAAF6FC

P698

Q35193215-381249B9-B4F7-4759-AD18-A1948D247DD6

P921

Q35193215-B56FB5E3-714D-4755-B047-A6F9EB4C99F3

P932

Q35193215-AA7A9A39-E873-46B3-9C80-96954BC28D2B

P356

P1433

Genes & Development

P1476

LRH-1 and PTF1-L coregulate an ...... network for digestive function

@en

P2093

Galvin H Swift

http://www.w3.org/2001/XMLSchema#string

Raymond J MacDonald

http://www.w3.org/2001/XMLSchema#string

Sam R Holmstrom

http://www.w3.org/2001/XMLSchema#string

Steven A Kliewer

http://www.w3.org/2001/XMLSchema#string

Tye Deering

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a nuclear receptor for bile acids

PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein

DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists

Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)

Overview of image analysis, image importing, and image processing using freeware

RBP-L, a transcription factor related to RBP-Jkappa

Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas

Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development.

The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element

P304

1674-1679

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.16860911

http://www.w3.org/2001/XMLSchema#string

P433

16

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P50

Frank J Poelwijk

David J Mangelsdorf

P577

2011-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51581652

http://www.w3.org/2001/XMLSchema#string

P698

21852532

http://www.w3.org/2001/XMLSchema#string

P921

Aizkuņģa dziedzeris

P932

3165932

http://www.w3.org/2001/XMLSchema#string