APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
about
Amyloid precursor protein and amyloid precursor-like protein 2 in cancerInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseAmyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegenerationAPP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functionsLow molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity(-)-Epigallocatechin-3-gallate ameliorates learning and memory deficits by adjusting the balance of TrkA/p75NTR signaling in APP/PS1 transgenic mice.A new molecular explanation for age-related neurodegeneration: the Tyr682 residue of amyloid precursor proteinThe Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease NeuropathologyVisualization and quantification of APP intracellular domain-mediated nuclear signaling by bimolecular fluorescence complementation.APP regulates NGF receptor trafficking and NGF-mediated neuronal differentiation and survival.Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.NGF, brain and behavioral plasticity.Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance.Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy.APP Receptor? To Be or Not To Be.NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis.Redundancy and divergence in the amyloid precursor protein family.NGF/TrkA Signaling as a Therapeutic Target for Pain.New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies.Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele.Paradoxical effect of TrkA inhibition in Alzheimer's disease models.Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function.The amyloid precursor protein modulates α2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment.
P2860
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P2860
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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2011年论文
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2011年论文
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name
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@ast
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@en
type
label
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@ast
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@en
prefLabel
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@ast
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@en
P2093
P2860
P50
P1476
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
@en
P2093
Alessia P M Barbagallo
Fulvio Florenzano
Maria T Ciotti
P2860
P304
11756-11761
P356
10.1523/JNEUROSCI.1960-11.2011
P407
P50
P577
2011-08-01T00:00:00Z