Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.
about
Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyNotch Signaling in Pancreatic DevelopmentNatural history of β-cell adaptation and failure in type 2 diabetesPtf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanismMind bomb 1 is required for pancreatic β-cell formationDifferent levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors.Noninvasive in vivo imaging of embryonic β-cell development in the anterior chamber of the eyeOxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha.Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development.Primary cilia in pancreatic development and disease.Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.Exposure of mouse embryonic pancreas to metformin enhances the number of pancreatic progenitorsCompetence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas developmentNotch-mediated patterning and cell fate allocation of pancreatic progenitor cells.Early pancreatic islet fate and maturation is controlled through RBP-JκNotch signaling in the pancreas: patterning and cell fate specification.Transcriptional control of mammalian pancreas organogenesis.Recent advances and prospects in the differentiation of pancreatic cells from human embryonic stem cells.Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine.Gene expression signature predicts human islet integrity and transplant functionality in diabetic mice.Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epitheliumDevelopment and regeneration in the endocrine pancreasNotch Signaling in Development, Tissue Homeostasis, and Disease.Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells.A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.
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P2860
Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Presenilins, Notch dose contro ...... a narrow developmental window.
@en
Presenilins, Notch dose contro ...... a narrow developmental window.
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type
label
Presenilins, Notch dose contro ...... a narrow developmental window.
@en
Presenilins, Notch dose contro ...... a narrow developmental window.
@nl
prefLabel
Presenilins, Notch dose contro ...... a narrow developmental window.
@en
Presenilins, Notch dose contro ...... a narrow developmental window.
@nl
P2860
P356
P1433
P1476
Presenilins, Notch dose contro ...... a narrow developmental window.
@en
P2093
M Alan Permutt
P2860
P304
P356
10.1101/GAD.1800209
P577
2009-09-01T00:00:00Z