γ-Secretase-Dependent Proteolysis of Transmembrane Domain of Amyloid Precursor Protein: Successive Tri- and Tetrapeptide Release in Amyloid β-Protein Production
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Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's DiseaseIdentification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.γ-Secretase processing and effects of γ-secretase inhibitors and modulators on long Aβ peptides in cells.Pharmacological targeting of the β-amyloid precursor protein intracellular domain.Structural biology of presenilins and signal peptide peptidases.Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.Structural and biochemical differences between the Notch and the amyloid precursor protein transmembrane domains.Alanine substitutions in the GXXXG motif alter C99 cleavage by γ-secretase but not its dimerization.Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes.Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in
P2860
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P2860
γ-Secretase-Dependent Proteolysis of Transmembrane Domain of Amyloid Precursor Protein: Successive Tri- and Tetrapeptide Release in Amyloid β-Protein Production
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
γ-Secretase-Dependent Proteoly ...... n Amyloid β-Protein Production
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type
label
γ-Secretase-Dependent Proteoly ...... n Amyloid β-Protein Production
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prefLabel
γ-Secretase-Dependent Proteoly ...... n Amyloid β-Protein Production
@en
P2860
P356
P1476
γ-Secretase-Dependent Proteoly ...... n Amyloid β-Protein Production
@en
P2093
Mako Takami
Satoru Funamoto
P2860
P304
P356
10.1155/2012/591392
P577
2012-12-31T00:00:00Z